Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.

Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.

Item
http://www.wikidata.org/entity/Q33381991
Monoclonal antibody-based therapies for microbial diseasesEvaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2.Antibody recognition of Shiga toxins (Stxs): computational identification of the epitopes of Stx2 subunit A to the antibodies 11E10 and S2C4Development and characterization of recombinant antibody fragments that recognize and neutralize in vitro Stx2 toxin from Shiga toxin-producing Escherichia coli.Single Chain Variable Fragments Produced in Escherichia coli against Heat-Labile and Heat-Stable Toxins from Enterotoxigenic E. coli.Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway.Monoclonal antibody 11E10, which neutralizes shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin.Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of Escherichia coli O157:H7-infected BALB/c mice.Characterization of enterohemorrhagic Escherichia coli O157:H7 00B015: a Shiga toxin producing but virulence-attenuated isolate.
P2860

Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.

Item
http://www.wikidata.org/entity/Q33381991
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@ast
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@en
type
label
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@ast
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@en
prefLabel
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@ast
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
@en
P2093
P304
P31
P356
10.1016/J.IMLET.2008.09.008
P433
P478
P577
P698