Monoclonal antibody 11E10, which neutralizes shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin.
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Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2?Antibodies for biodefenseBaicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.H-NS Mutation-Mediated CRISPR-Cas Activation Inhibits Phage Release and Toxin Production of Escherichia coli Stx2 Phage Lysogen.Evaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2.Enhanced virulence of the Escherichia coli O157:H7 spinach-associated outbreak strain in two animal models is associated with higher levels of Stx2 production after induction with ciprofloxacin.Identification of amino acids critical for the cytotoxicity of Shiga toxin 1 and 2 in Saccharomyces cerevisiae.Development of monoclonal antibodies and immunoassays for sensitive and specific detection of Shiga toxin Stx2f.Antibody recognition of Shiga toxins (Stxs): computational identification of the epitopes of Stx2 subunit A to the antibodies 11E10 and S2C4Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodiesDietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and diseaseEvaluation of recombinant forms of the shiga toxin variant Stx2eB subunit and non-toxic mutant Stx2e as vaccine candidates against porcine edema disease.Oral intoxication of mice with Shiga toxin type 2a (Stx2a) and protection by anti-Stx2a monoclonal antibody 11E10.Antibody-mediated inhibition of ricin toxin retrograde transport.Shiga toxins: from structure and mechanism to applications.Peptides derived from phage display libraries as potential neutralizers of Shiga toxin-induced cytotoxicity in vitro and in vivoImmunoassay
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Monoclonal antibody 11E10, which neutralizes shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
@en
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
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type
label
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
@en
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
@nl
prefLabel
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
@en
Monoclonal antibody 11E10, whi ...... lar distribution of the toxin.
@nl
P2093
P2860
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P1476
Monoclonal antibody 11E10, whi ...... ular distribution of the toxin
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Angela R Melton-Celsa
Cory M Robinson
Humberto M Carvalho
James F Sinclair
Michael J Smith
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P304
P356
10.1128/IAI.00005-09
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P577
2009-05-11T00:00:00Z