The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.
about
AID and APOBECs span the gap between innate and adaptive immunityNatural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivityAPOBEC3 proteins mediate the clearance of foreign DNA from human cellsGenetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivoStructure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activitiesHuman and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1The localization of APOBEC3H variants in HIV-1 virions determines their antiviral activityCrystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfacesPrototype foamy virus Bet impairs the dimerization and cytosolic solubility of human APOBEC3GThe range of human APOBEC3H sensitivity to lentiviral Vif proteinsHow Active Are Porcine Endogenous Retroviruses (PERVs)?The APOBEC3 family of retroelement restriction factorsEvolutionary conflicts between viruses and restriction factors shape immunitySuppression of APOBEC3-mediated restriction of HIV-1 by VifCrystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding DomainAID/APOBEC deaminases and cancerA naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentivirusesFootprint of APOBEC3 on the genome of human retroelementsIntrinsic immunity against retrotransposons by APOBEC cytidine deaminasesAn ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammalsAPOBEC3B and AID have similar nuclear import mechanisms.Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities.Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.Are viruses inhibited by APOBEC3 molecules from their host species?Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity.A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif.Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS.Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3APOBEC3B, a molecular driver of mutagenesis in human cancers.Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restrictionLentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity.Evolution of orthologous tandemly arrayed gene clusters.Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to VifCore-binding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation.A single amino acid in human APOBEC3F alters susceptibility to HIV-1 VifImmunogenetics of small ruminant lentiviral infectionsSomatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism.Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities.Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons.Correlation of APOBEC3 in tumor tissues with clinico-pathological features and survival from hepatocellular carcinoma after curative hepatectomy.
P2860
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P2860
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@ast
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@en
type
label
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@ast
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@en
prefLabel
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@ast
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@en
P2093
P2860
P356
P1476
The artiodactyl APOBEC3 innate ...... ancestor of placental mammals.
@en
P2093
Denis Bertrand
Isidro Hötzel
Kevin A T Silverstein
Mathieu Lajoie
Nadia El-Mabrouk
Rebecca S LaRue
Stefán R Jónsson
Timothy P L Smith
Valgerdur Andrésdóttir
P2860
P2888
P356
10.1186/1471-2199-9-104
P577
2008-11-18T00:00:00Z
P5875
P6179
1020631443