APOBEC3 proteins mediate the clearance of foreign DNA from human cells
about
AID and APOBECs span the gap between innate and adaptive immunityGenetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivoAPOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activitiesHuman and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3GMutational processes molding the genomes of 21 breast cancersHuman LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activityPost-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic CellsAssociations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review)Anti-HBV Drugs: Progress, Unmet Needs, and New HopeThe APOBEC3 family of retroelement restriction factorsCrystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding DomainNMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificityEvasion of host immune defenses by human papillomavirusAID/APOBEC deaminases and cancerImmune-Regulatory Events in the Clearance of HBsAg in Chronic Hepatitis B: Focuses on HLA-DPMolecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancerAPOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcriptsEndogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2nInhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3GA DNA sequence recognition loop on APOBEC3A controls substrate specificityInteraction of APOBEC3A with DNA assessed by atomic force microscopyThe interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombinationLEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivityHIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes.Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damageMassive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival.Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.Is homologous recombination really an error-free process?APOBEC3B, a molecular driver of mutagenesis in human cancers.Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytesNon-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions.Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restrictionReplication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNAAPOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitnessInnate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms
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P2860
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@ast
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en-gb
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@nl
type
label
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@ast
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en-gb
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@nl
prefLabel
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@ast
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en-gb
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@nl
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APOBEC3 proteins mediate the clearance of foreign DNA from human cells
@en
P2093
Joy Lengyel
Mark D Stenglein
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P356
10.1038/NSMB.1744
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P577
2010-02-01T00:00:00Z
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P6179
1002558962