Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.
about
Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.Inherited thrombocytopenias: an approach to diagnosis and management.Unique in vitro and in vivo thrombopoietic activities of ingenol 3,20 dibenzoate, a Ca(++)-independent protein kinase C isoform agonist.Intrinsically impaired platelet production in some patients with persistent or chronic immune thrombocytopenia.Fli1 acts downstream of Etv2 to govern cell survival and vascular homeostasis via positive autoregulation.Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activityBAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.Identification of a novel, tissue-specific ABCG2 promoter expressed in pediatric acute megakaryoblastic leukemia.Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome.Integration of Elf-4 into stem/progenitor and erythroid regulatory networks through locus-wide chromatin studies coupled with in vivo functional validationBET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.Exploring the Functional Disorder and Corresponding Key Transcription Factors in Intraductal Papillary Mucinous Neoplasms Progression.Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.Endothelial Erg expression is required for embryogenesis and vascular integrityERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemiaETS transcription factors in embryonic vascular development.Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.Genomic and biochemical insights into the specificity of ETS transcription factors.Mouse models of diseases of megakaryocyte and platelet homeostasis.The ets transcription factor Fli-1 in development, cancer and disease.A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.Interplay of transcription factors and microRNAs during embryonic hematopoiesis.Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program.The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell DevelopmentArticular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.The ERGonomics of hematopoietic stem cell self-renewal.MEIS1 regulates early erythroid and megakaryocytic cell fate.Ets family protein, erg expression in developing and adult mouse tissues by a highly specific monoclonal antibody.DNA methylation at enhancers identifies distinct breast cancer lineages.Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma.
P2860
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P2860
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@ast
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@en
type
label
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@ast
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@en
prefLabel
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@ast
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@en
P2093
P2860
P50
P356
P1476
Dual requirement for the ETS t ...... and the megakaryocyte lineage.
@en
P2093
Dennis K Watson
Elizabeth A Kruse
Paquita Nurden
Stephen J Loughran
Tracey M Baldwin
Warren S Alexander
P2860
P304
13814-13819
P356
10.1073/PNAS.0906556106
P407
P577
2009-07-31T00:00:00Z