Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. - Wikidata - awgldk - TriplyDB

Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.

Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.

http://www.wikidata.org/entity/Q33387162

about

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?Metabolic targeting of lactate efflux by malignant glioma inhibits invasiveness and induces necrosis: an in vivo study Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Reexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effect Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters Tissue elasticity regulated tumor gene expression: implication for diagnostic biomarkers of primitive neuroectodermal tumor Non-invasive metabolic imaging of brain tumours in the era of precision medicine.Regulation of pyruvate metabolism and human disease Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer.Lactate production by the mammalian blastocyst: manipulating the microenvironment for uterine implantation and invasion?RNAi targeting CXCR4 inhibits tumor growth through inducing cell cycle arrest and apoptosis.Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms.Nanoparticles for Targeting Intratumoral Hypoxia: Exploiting a Potential Weakness of Glioblastoma.Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor.Role of integrins in regulating proteases to mediate extracellular matrix remodeling Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets Natural compounds as regulators of the cancer cell metabolism Lactate, a Neglected Factor for Diabetes and Cancer Interaction.Tumors as organs: biologically augmenting radiation therapy by inhibiting transforming growth factor β activity in carcinomas.The tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms.Systemic Activin signaling independently regulates sugar homeostasis, cellular metabolism, and pH balance in Drosophila melanogaster.Neuronal-astrocyte metabolic interactions: understanding the transition into abnormal astrocytoma metabolism.Novel ways to target brain tumour metabolism.Exploiting metabolic differences in glioma therapy.The molecular profile of microglia under the influence of glioma.The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas How does cancer cell metabolism affect tumor migration and invasion?Cancer metabolomics in basic science perspective.Transforming growth factor β and bone morphogenetic protein actions in brain tumors.The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor.Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.Limited role for transforming growth factor-β pathway activation-mediated escape from VEGF inhibition in murine glioma models.Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells.Lactate at the crossroads of metabolism, inflammation, and autoimmunity.

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P2860

Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.

http://www.wikidata.org/entity/Q33387162

description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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type

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Lactate promotes glioma migrat ...... of matrix metalloproteinase-2.

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Anett Doerfelt

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Anja-Katrin Bosserhoff

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Christoph P Beier

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Fusun Baumann

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Katja Dettmer

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Marina Kreutz

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Michael Kastenberger

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Peter J Oefner

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Petra Leukel

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P2860

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

Epithelial-mesenchymal transitions in tumour progression

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.

Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1).

Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.

The role of matrix metalloproteinase genes in glioma invasion: co-dependent and interactive proteolysis.

Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo

Lactate as a pivotal element in neuron-glia metabolic cooperation.

Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion.

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368-380

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10.1215/15228517-2008-106

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4

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11

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Thomas Nickl-Jockschat

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23497275

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19033423

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2743217

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