Multistable decision switches for flexible control of epigenetic differentiation.
about
MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determinationImplications of the Hybrid Epithelial/Mesenchymal Phenotype in MetastasisMolecular signaling network motifs provide a mechanistic basis for cellular threshold responsesLarge-scale analysis of network bistability for human cancersIntrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic SwitchesClassification of transient behaviours in a time-dependent toggle switch modelEngineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination.A mathematical model for the reciprocal differentiation of T helper 17 cells and induced regulatory T cellsComputational design of synthetic regulatory networks from a genetic library to characterize the designability of dynamical behaviorsA dynamical model of oocyte maturation unveils precisely orchestrated meiotic decisions.The sensitivity of memory consolidation and reconsolidation to inhibitors of protein synthesis and kinases: computational analysisSpeed-dependent cellular decision making in nonequilibrium genetic circuits.Strategic cell-cycle regulatory features that provide mammalian cells with tunable G1 length and reversible G1 arrest.A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells.Interplay between path and speed in decision making by high-dimensional stochastic gene regulatory networks.Dynamical principles of cell-cycle arrest: reversible, irreversible, and mixed strategies.Towards elucidating the connection between epithelial-mesenchymal transitions and stemnessDynamic and structural constraints in signal propagation by regulatory networks.Competition in notch signaling with cis enriches cell fate decisions.Bifurcation dynamics and determination of alternate cell fates in bipotent progenitor cellsReliable binary cell-fate decisions based on oscillations.Motifs emerge from function in model gene regulatory networks.A Mathematical Framework for Understanding Four-Dimensional Heterogeneous Differentiation of CD4+ T CellsA Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic CuesA computational method for the investigation of multistable systems and its application to genetic switches.Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching timesCoupling the modules of EMT and stemness: A tunable 'stemness window' modelCell Fate Specification Based on Tristability in the Inner Cell Mass of Mouse Blastocysts.A physical mechanism of cancer heterogeneityPeriodic, Quasi-periodic and Chaotic Dynamics in Simple Gene Elements with Time Delays.Principles of dynamical modularity in biological regulatory networks.Realization of tristability in a multiplicatively coupled dual-loop genetic network.Bifurcation-based approach reveals synergism and optimal combinatorial perturbation.Genes at work in random bouts: stochastically discontinuous gene activity makes cell cycle duration and cell fate decisions variable, thus providing for stem cells plasticity.Bursting noise in gene expression dynamics: linking microscopic and mesoscopic models.Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro.Pattern selection by dynamical biochemical signals.Exact time-dependent solutions for a self-regulating gene.Variable renewal rate and growth properties of cell populations in colon crypts.
P2860
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P2860
Multistable decision switches for flexible control of epigenetic differentiation.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Multistable decision switches for flexible control of epigenetic differentiation.
@ast
Multistable decision switches for flexible control of epigenetic differentiation.
@en
type
label
Multistable decision switches for flexible control of epigenetic differentiation.
@ast
Multistable decision switches for flexible control of epigenetic differentiation.
@en
prefLabel
Multistable decision switches for flexible control of epigenetic differentiation.
@ast
Multistable decision switches for flexible control of epigenetic differentiation.
@en
P2860
P1476
Multistable decision switches for flexible control of epigenetic differentiation.
@en
P2093
Juan F Poyatos
Raúl Guantes
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000235
P577
2008-11-28T00:00:00Z