Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. - Wikidata - awgldk - TriplyDB

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

http://www.wikidata.org/entity/Q33389875

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Blood Vitamin D Levels in Relation to Genetic Estimation of African Ancestry Genomic screening with RNAi: results and challenges High content screening in chemical biology: overview and main challenges Dysfunction of Autophagy: A Possible Mechanism Involved in the Pathogenesis of Vitiligo by Breaking the Redox Balance of Melanocytes Adapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in Melanoma Cell-Based Assay Design for High-Content Screening of Drug Candidates RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J Autophagy is essential for mouse sense of balance A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy.Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.Identification of glycogen synthase kinase 3α as a therapeutic target in melanoma [6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway.Networks and pathways in pigmentation, health, and disease.Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices Atg7 is required for acrosome biogenesis during spermatogenesis in mice Signaling pathways in melanosome biogenesis and pathology Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling Reactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.siRNA high-throughput kinase library screen identifies protein kinase, DNA-activated catalytic polypeptide to play a role in MyD88-induced IFNA2 activation and IL-8 secretion.Suppression of dendritic cell-mediated responses by genes in calcium and cysteine protease pathways during Mycobacterium tuberculosis infection.Signals from the lysosome: a control centre for cellular clearance and energy metabolism.Maintenance of melanophore morphology and survival is cathepsin and vps11 dependent in zebrafish.WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.ULK1 regulates melanin levels in MNT-1 cells independently of mTORC1.Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.Autophagy proteins regulate the secretory component of osteoclastic bone resorption.Vigilance and validation: Keys to success in RNAi screening.Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster.Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle.Mechanisms of protein delivery to melanosomes in pigment cells.Autophagy as a melanocytic self-defense mechanism Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur.Microtubule-associated protein light chain 3 is involved in melanogenesis via regulation of MITF expression in melanocytes 9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis.Targeting ALDH1A1 to treat pigmentary disorders.

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Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

http://www.wikidata.org/entity/Q33389875

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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type

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Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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Genome-wide siRNA-based functi ...... melanogenesis in human cells.

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Genome-wide siRNA-based functi ...... t melanogenesis in human cells

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Anand K Ganesan

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Brian Bodemann

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Hsiang Ho

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Jayavani Aruri

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Michael A White

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Shiney Koshy

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Tatiana Krasieva

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Zachary Richardson

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P2860

What controls variation in human skin color?

Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Melanosomes--dark organelles enlighten endosomal membrane transport

Autophagy in the Pathogenesis of Disease

Autophagy fights disease through cellular self-digestion

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins

Genetic determinants of hair, eye and skin pigmentation in Europeans

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e1000298

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10.1371/JOURNAL.PGEN.1000298

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12

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Patrick J. Farmer

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