Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466.
about
Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestisAdaptation of an L-proline adenylation domain to use 4-propyl-L-proline in the evolution of lincosamide biosynthesisArtificial chromosomes to explore and to exploit biosynthetic capabilities of actinomycetes.Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycinLincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family.Phylogenetic relatedness determined between antibiotic resistance and 16S rRNA genes in actinobacteria.Lincosamide synthetase--a unique condensation system combining elements of nonribosomal peptide synthetase and mycothiol metabolism.An efficient intergeneric conjugation of DNA from Escherichia coli to mycelia of the lincomycin-producer Streptomyces lincolnensis.Construction of the octose 8-phosphate intermediate in lincomycin A biosynthesis: characterization of the reactions catalyzed by LmbR and LmbN.The biosynthesis of nitrogen-, sulfur-, and high-carbon chain-containing sugars.In vitro characterization of LmbK and LmbO: identification of GDP-D-erythro-α-D-gluco-octose as a key intermediate in lincomycin A biosynthesis.Identification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2).Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces SpeciesNew Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a γ-Glutamyltransferase Cleave the C-C Bond?Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.Deacetylation of mycothiol-derived 'waste product' triggers the last biosynthetic steps of lincosamide antibiotics.4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavageMetabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.Sequence analysis of porothramycin biosynthetic gene cluster.Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci.Characterization of Enzymes Catalyzing Transformations of Cysteine S-Conjugated Intermediates in the Lincosamide Biosynthetic Pathway.The novel transcriptional regulator LmbU promotes lincomycin biosynthesis through regulating expression of its target genes in Streptomyces lincolnensis.Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.Isolation and characterization of indigenous Streptomyces and Lentzea strains from soils containing boron compounds in Argentina.Mutational biosynthesis of neomycin analogs by a mutant of neomycin-producing Streptomyces fradiae.Novel pathway of 3-hydroxyanthranilic acid formation in limazepine biosynthesis reveals evolutionary relation between phenazines and pyrrolobenzodiazepines.
P2860
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P2860
Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@ast
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@en
type
label
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@ast
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@en
prefLabel
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@ast
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@en
P2093
P1433
P1476
Sequence analysis and heterolo ...... myces lincolnensis ATCC 25466.
@en
P2093
J Olsovská
M Jelínková
M Koberská
P2888
P304
P356
10.1007/S12223-008-0060-8
P50
P577
2008-12-16T00:00:00Z
P5875
P6179
1049423053