Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.
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Bacillithiol: a key protective thiol in Staphylococcus aureusStructure of the Ergothioneine-Biosynthesis Amidohydrolase EgtCRedox regulation by reversible protein S-thiolation in bacteriaRecent advances in the elucidation of enzymatic function in natural product biosynthesisC-S bond cleavage by a polyketide synthase domain.Elucidation of salicylate attachment in celesticetin biosynthesis opens the door to create a library of more efficient hybrid lincosamide antibioticsLinking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking.Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and InfectivityIdentification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2).Genome Engineering and Modification Toward Synthetic Biology for the Production of Antibiotics.Mycothiol synthesis by an anomerization reaction through endocyclic cleavage.New Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a γ-Glutamyltransferase Cleave the C-C Bond?Use of Antibiotics and Antimicrobial Resistance in Veterinary Medicine as Exemplified by the Swine Pathogen Streptococcus suis.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Role of Ergothioneine in Microbial Physiology and Pathogenesis.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.Deacetylation of mycothiol-derived 'waste product' triggers the last biosynthetic steps of lincosamide antibiotics.4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavageCharacterization of Enzymes Catalyzing Transformations of Cysteine S-Conjugated Intermediates in the Lincosamide Biosynthetic Pathway.Production of ergothioneine by Methylobacterium species.The novel transcriptional regulator LmbU promotes lincomycin biosynthesis through regulating expression of its target genes in Streptomyces lincolnensis.The versatile low-molecular-weight thiols: Beyond cell protection.Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.Thiol Redox and pKa Properties of Mycothiol, the Predominant Low-Molecular-Weight Thiol Cofactor in the Actinomycetes.Electrochemical impedance analysis of perovskite-electrolyte interfaces.Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis.The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry.Enhancement of antibiotic productions by engineered nitrate utilization in actinomycetes.Improvement of lincomycin production by mutant selection and metabolic regulation.Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis.Redox regulation by reversible protein S-thiolation in Gram-positive bacteria
P2860
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P2860
Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Metabolic coupling of two smal ...... biosynthesis of lincomycin A.
@en
type
label
Metabolic coupling of two smal ...... biosynthesis of lincomycin A.
@en
prefLabel
Metabolic coupling of two smal ...... biosynthesis of lincomycin A.
@en
P2093
P2860
P356
P1433
P1476
Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A
@en
P2093
Dongxiao Xu
Qinglin Zhang
Qunfei Zhao
P2860
P2888
P304
P356
10.1038/NATURE14137
P407
P50
P577
2015-01-14T00:00:00Z
P6179
1015331547