Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors. - Wikidata - awgldk - TriplyDB

Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.

Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.

http://www.wikidata.org/entity/Q33404652

about

Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain Antitumoral activity of snake venom proteins: new trends in cancer therapy Swing-out of the β3 hybrid domain is required for αIIbβ3 priming and normal cytoskeletal reorganization, but not adhesion to immobilized fibrinogen Metalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction Sites Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa Evaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesion Arg-Tyr-Asp (RYD) and Arg-Cys-Asp (RCD) motifs in dendroaspin promote selective inhibition of beta1 and beta3 integrins Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3 A family of cellular proteins related to snake venom disintegrins Lebestatin, a disintegrin from Macrovipera venom, inhibits integrin-mediated cell adhesion, migration and angiogenesis Destabilizing loop swaps in the CDRs of an immunoglobulin VL domain.Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.Function of disintegrin-like/cysteine-rich domains of atrolysin A. Inhibition of platelet aggregation by recombinant protein and peptide antagonists.alpha 2beta 1 integrin is not recognized by rhodocytin but is the specific, high affinity target of rhodocetin, an RGD-independent disintegrin and potent inhibitor of cell adhesion to collagen.Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells.Platelet-adenovirus vs. inert particles interaction: effect on aggregation and the role of platelet membrane receptors.Salivary transcriptome of the North American medicinal leech, Macrobdella decora.Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cells Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3.Integrin alpha(v)beta(3)-Targeted Cancer Therapy.Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography Laboratory reptile surgery: principles and techniques.Prevention of thrombosis and rethrombosis and enhancement of the thrombolytic actions of recombinant tissue-type plasminogen activator in the canine heart by DMP728, a glycoprotein IIb/IIIa antagonist Integrin targeted therapeutics.Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules.The human platelet fibrinogen receptor: clinical and therapeutic significance.Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway The cleaved peptide of the thrombin receptor is a strong platelet agonist.Differences in binding of (99m)Tc-disintegrins to integrin alphavbeta3 on tumor and vascular cells.Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates alpha2beta1 integrin-mediated cell adhesion, migration and proliferation.Brainstem and other malignant gliomas: II. Possible mechanisms of brain infiltration by tumor cells.Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor.Platelets and fibrinolysis.Comparative analysis of the venom proteome of four important Malaysian snake species.Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth.Novel antithrombotic therapy.Eptifibatide: a potent inhibitor of the platelet receptor integrin, glycoprotein IIb/IIIa.The exchange of Arg-Gly-Asp (RGD) and Arg-Tyr-Asp (RYD) binding sequences in a recombinant murine Fab fragment specific for the integrin alpha IIb beta 3 does not alter integrin recognition.Molecular cloning and expression of catrocollastatin, a snake-venom protein from Crotalus atrox (western diamondback rattlesnake) which inhibits platelet adhesion to collagen.Contortrostatin, a dimeric disintegrin from Agkistrodon contortrix contortrix, inhibits breast cancer progression.

P2860

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P2860

Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.

http://www.wikidata.org/entity/Q33404652

description

1990 nî lūn-bûn

@nan

1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1990 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1990年の論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年论文

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name

Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

@ast

Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

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type

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Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

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Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

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Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

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Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

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Proceedings of the National Academy of Sciences of the United States of America

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Platelet glycoprotein IIb-IIIa ...... atelet-aggregation inhibitors.

@en

P2093

Bunting S

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Deisher TA

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Dennis MS

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Henzel WJ

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Lazarus RA

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Lipari MT

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Napier MA

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Pitti RM

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P2860

New perspectives in cell adhesion: RGD and integrins

Integrins: a family of cell surface receptors

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin

Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors

Ligand: a versatile computerized approach for characterization of ligand-binding systems

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor.

Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.

Expression of recombinant platelet glycoprotein IIbIIIa results in a functional fibrinogen-binding complex.

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2471-2475

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10.1073/PNAS.87.7.2471

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7

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87

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1990-04-01T00:00:00Z

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20834656

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2320569

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53711

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