Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42.
about
Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationLIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.TUBB1 mutation disrupting microtubule assembly impairs proplatelet formation and results in congenital macrothrombocytopenia.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.Progress in understanding the diagnosis and molecular genetics of macrothrombocytopenias.Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors.The role of bone marrow microenvironment in platelet production and their implications for the treatment of thrombocytopenic diseases.The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice.Platelet-neutrophil interactions under thromboinflammatory conditionsRegulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis.Platelet Rho GTPases-a focus on novel players, roles and relationships.Integrin αIIbβ3 outside-in signaling.Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes.New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach.The Hippo-p53 pathway in megakaryopoiesis.Nbeal2 interacts with Dock7, Sec16a, and Vac14.Bortezomib for the treatment of multiple myeloma.Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach.The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation.Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.Imaging platelet biogenesis in vivoMicrotubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation
P2860
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P2860
Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@ast
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@en
type
label
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@ast
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@en
prefLabel
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@ast
Defective tubulin organization ...... ocytes lacking Rac1 and Cdc42.
@en
P2093
P1433
P1476
Defective tubulin organization ...... yocytes lacking Rac1 and Cdc42
@en
P2093
Bernhard Nieswandt
Christian Gachet
Deya Cherpokova
Georg Krohne
Harald Schulze
Imke Meyer
Irina Pleines
Martina Morowski
Najet Debili
Sebastian Dütting
P304
P356
10.1182/BLOOD-2013-03-487942
P407
P577
2013-07-16T00:00:00Z