The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.
about
Click chemistry in complex mixtures: bioorthogonal bioconjugationOpportunities for functional selectivity in GPCR antibodiesEncoding asymmetry of the N-glycosylation motif facilitates glycoprotein evolutionSmall Molecule Inhibition of the TNF Family Cytokine CD40 Ligand through a Subunit Fracture MechanismTeaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 ScaffoldThe crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibodyDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicityEffects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragmentsSpecific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody FragmentPrinciples of agonist recognition in Cys-loop receptorsPrediction of site-specific interactions in antibody-antigen complexes: the proABC method and serverStructural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal AntibodiesProtein tyrosine nitration: biochemical mechanisms and structural basis of functional effects.Glucose oxidase stabilization against thermal inactivation using high hydrostatic pressure and hydrophobic modification.The full amino acid repertoire is superior to serine/tyrosine for selection of high affinity immunoglobulin G binders from the fibronectin scaffoldIdentification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display.Monobodies and other synthetic binding proteins for expanding protein sciencePhage display and molecular imaging: expanding fields of vision in living subjects.Origins of specificity and affinity in antibody-protein interactionsIdentification of nitrated immunoglobulin variable regions in the HIV-infected human brain: implications in HIV infection and immune response.Transthyretin-derived peptides as β-amyloid inhibitors.Selection of a CXCR4 antagonist from a human heavy chain CDR3-derived phage library.Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions.Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment.Structural anatomy of telomere OB proteinsTunable control of polyproline helix (PPII) structure via aromatic electronic effects: an electronic switch of polyproline helix.Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies.Structural insights for engineering binding proteins based on non-antibody scaffoldsA novel C-terminal region within the multicargo type III secretion chaperone CesT contributes to effector secretion.Protein engineering with biosynthesized libraries from Bordetella bronchiseptica bacteriophageStructure-affinity properties of a high-affinity ligand of FKBP12 studied by molecular simulations of a binding intermediateIdentification and analysis of conserved pockets on protein surfacesComputational design of affinity and specificity at protein-protein interfacesA novel heavy domain antibody library with functionally optimized complementarity determining regions.Tentative identification of the second substrate binding site in Arabidopsis phytochelatin synthaseThe impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.Identification of Tyr residues that enhance folate substrate binding and constrain oscillation of the proton-coupled folate transporter (PCFT-SLC46A1).Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes.High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin DomainsPore-exposed tyrosine residues of P-glycoprotein are important hydrogen-bonding partners for drugs.
P2860
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P2860
The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The importance of being tyrosi ...... st synthetic binding proteins.
@ast
The importance of being tyrosi ...... st synthetic binding proteins.
@en
type
label
The importance of being tyrosi ...... st synthetic binding proteins.
@ast
The importance of being tyrosi ...... st synthetic binding proteins.
@en
prefLabel
The importance of being tyrosi ...... st synthetic binding proteins.
@ast
The importance of being tyrosi ...... st synthetic binding proteins.
@en
P2860
P356
P1433
P1476
The importance of being tyrosi ...... st synthetic binding proteins.
@en
P2093
Sachdev S Sidhu
P2860
P304
P356
10.1021/CB800314V
P50
P577
2009-05-01T00:00:00Z