Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors.
about
Morphoproteomics and biomedical analytics confirm the mTORC2/Akt pathway as a resistance signature and activated ERK and STAT3 as concomitant prosurvival/antiapoptotic pathways in metastatic renal cell carcinoma (RCC) progressing on rapalogs: pathogHDACs and HDAC Inhibitors in Cancer Development and Therapy.HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells.RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition.mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression
P2860
Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@ast
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@en
type
label
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@ast
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@en
prefLabel
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@ast
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@en
P2093
P2860
P1476
Phase I study of the mTOR inhi ...... cinoma and other solid tumors.
@en
P2093
Alycia Corrigan
Anthony J Olszanski
Colleen H Tetzlaff
Crystal S Denlinger
Elizabeth R Plimack
Karthik Devarajan
Lois Malizzia
Matthew Zibelman
Susan K Roethke
Yu-Ning Wong
P2860
P2888
P304
P356
10.1007/S10637-015-0261-3
P577
2015-06-20T00:00:00Z
P6179
1036474224