about
Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressantsTargeting tumorigenesis: development and use of mTOR inhibitors in cancer therapyOsteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cellsThe regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionOverexpression of s6 kinase 1 in brain tumours is associated with induction of hypoxia-responsive genes and predicts patients' survivalPPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancerThe transcription factor Engrailed-2 guides retinal axonsCarboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTORGene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.Identification of Map4k4 as a novel suppressor of skeletal muscle differentiationCCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivityEssential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signallingHDAC6 and microtubules are required for autophagic degradation of aggregated huntingtinRegulation of mTOR and cell growth in response to energy stress by REDD1.Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationDrosophila lacking microRNA miR-278 are defective in energy homeostasisHypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismMammalian target of rapamycin: a central node of complex signaling cascadesFat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolismmTOR inhibitors in advanced renal cell carcinomaSpatial regulation of the mTORC1 system in amino acids sensing pathwayTargeting mTOR for the treatment of AML. New agents and new directionsThe mTOR signalling pathway in human cancerNext-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategySestrins at the crossroad between stress and agingMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesisThe TSC1-TSC2 complex: a molecular switchboard controlling cell growthmTOR signaling: at the crossroads of plasticity, memory and diseaseSpecification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathwayAmino acid transporter LAT3 is required for podocyte development and functionRheb and mTOR regulate neuronal polarity through Rap1BCalorie restriction and the exercise of chromatinA complex interplay between Akt, TSC2 and the two mTOR complexesHuman eukaryotic release factor 3a depletion causes cell cycle arrest at G1 phase through inhibition of the mTOR pathwayHypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttlingIdentification of Sin1 as an essential TORC2 component required for complex formation and kinase activityRole of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Upstream and downstream of mTOR
@ast
Upstream and downstream of mTOR
@en
Upstream and downstream of mTOR
@nl
type
label
Upstream and downstream of mTOR
@ast
Upstream and downstream of mTOR
@en
Upstream and downstream of mTOR
@nl
prefLabel
Upstream and downstream of mTOR
@ast
Upstream and downstream of mTOR
@en
Upstream and downstream of mTOR
@nl
P3181
P356
P1433
P1476
Upstream and downstream of mTOR
@en
P2093
Nissim Hay
P304
P3181
P356
10.1101/GAD.1212704
P407
P577
2004-08-15T00:00:00Z