about
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological SignificanceDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Systems Biology Approaches to Understand Natural Products BiosynthesisThe Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine MicroorganismsPrimer on agar-based microbial imaging mass spectrometryMotif-independent de novo detection of secondary metabolite gene clusters-toward identification from filamentous fungiExpanding our understanding of sequence-function relationships of type II polyketide biosynthetic gene clusters: bioinformatics-guided identification of Frankiamicin A from Frankia sp. EAN1pecGenomic charting of ribosomally synthesized natural product chemical space facilitates targeted miningComputational approaches to natural product discoveryImaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporusComputational identification and analysis of orphan assembly-line polyketide synthases.Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.SBSPKS: structure based sequence analysis of polyketide synthasesMarine natural products: a new wave of drugs?Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusterseSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes.Mining the metabiome: identifying novel natural products from microbial communities.PKMiner: a database for exploring type II polyketide synthasesGenome mining of Streptomyces ambofaciens.Metagenomic small molecule discovery methods.Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov modelsGenomic basis for natural product biosynthetic diversity in the actinomycetesMeta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria.Integrating '-omics' and natural product discovery platforms to investigate metabolic exchange in microbiomesPep2Path: automated mass spectrometry-guided genome mining of peptidic natural products.Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743.A mass spectrometry-guided genome mining approach for natural product peptidogenomics.antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clustersGenome mining and metabolic profiling of the rhizosphere bacterium Pseudomonas sp. SH-C52 for antimicrobial compounds.Phylogenetic approaches to natural product structure predictionFungal biodiversity to biotechnology.Using natural products for drug discovery: the impact of the genomics era.Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosisCharacterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivativeGenomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Automated genome mining for natural products.
@ast
Automated genome mining for natural products.
@en
type
label
Automated genome mining for natural products.
@ast
Automated genome mining for natural products.
@en
prefLabel
Automated genome mining for natural products.
@ast
Automated genome mining for natural products.
@en
P2093
P2860
P356
P1433
P1476
Automated genome mining for natural products
@en
P2093
David H Sherman
James Zajkowski
Michael H T Li
P2860
P2888
P356
10.1186/1471-2105-10-185
P577
2009-06-16T00:00:00Z
P5875
P6179
1049523926