Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas. - Wikidata - awgldk - TriplyDB

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

http://www.wikidata.org/entity/Q33486497

about

Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis TGF-β control of stem cell differentiation genes GEMMs as preclinical models for testing pancreatic cancer therapies Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads Mouse models of pancreatic cancer Partners in crime: The role of tandem modules in gene transcription Genetically engineered mouse models of pancreatic adenocarcinoma Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome A Poised Chromatin Platform for TGF-β Access to Master Regulators Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia TGFβ signalling in context Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma Dynamic regulation of Tgf-B signaling by Tif1γ: a computational approach.The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.Tumour suppressor TRIM33 targets nuclear β-catenin degradation TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients.Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.Brain expression of Cre recombinase driven by pancreas-specific promoters.Clinical characteristics of patients with anti-TIF1-γ antibodies Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution.Isolation and culture of mouse primary pancreatic acinar cells Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis Anti-transcription intermediary factor 1-gamma autoantibody ELISA development and validation Common pathways of autoimmune inflammatory myopathies and genetic neuromuscular disorders.Malignancy and idiopathic inflammatory myopathies SMAD4 and its role in pancreatic cancer.Association of overexpression of TIF1γ with colorectal carcinogenesis and advanced colorectal adenocarcinoma.A Comprehensive Overview on Myositis-Specific Antibodies: New and Old Biomarkers in Idiopathic Inflammatory Myopathy.Repression of TIF1γ by SOX2 promotes TGF-β-induced epithelial-mesenchymal transition in non-small-cell lung cancer.Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma.The TGF-β/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance.Cells of origin of pancreatic neoplasms.Genome profiling of pancreatic adenocarcinoma.Acute sensitivity of the oral mucosa to oncogenic K-ras.

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P2860

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

http://www.wikidata.org/entity/Q33486497

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@ast

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@en

type

label

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@ast

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@en

prefLabel

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@ast

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

@en

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JOURNAL.PGEN.1000575

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Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

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Bastien Kaniewski

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Fabien Gay

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Florian Lepinasse

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Isabelle Treilleux

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Juan L Iovanna

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Julien C Marie

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Kai-Ping Yan

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Nabeel Bardeesy

http://www.w3.org/2001/XMLSchema#string

Pierre Dubus

http://www.w3.org/2001/XMLSchema#string

Ruth Rimokh

http://www.w3.org/2001/XMLSchema#string

P2860

TIF1gamma, a novel member of the transcriptional intermediary factor 1 family

Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

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e1000575

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10.1371/JOURNAL.PGEN.1000575

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7

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5

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Nabeel Bardeesy

Laurent Bartholin

Jean-Yves Scoazec

David F Vincent

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2009-07-24T00:00:00Z

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26692403

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19629168

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Aizkuņģa dziedzeris

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2706992

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