Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityA PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombinationChk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restartRPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseThe role of RPA2 phosphorylation in homologous recombination in response to replication arrestRING finger and WD repeat domain 3 (RFWD3) associates with replication protein A (RPA) and facilitates RPA-mediated DNA damage response.Interplay of DNA damage and cell cycle signaling at the level of human replication protein AMore forks on the road to replication stress recoveryPhosphatases in the cellular response to DNA damage.Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans.Parvovirus infection-induced DNA damage responseThe DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.Regulation of Rfa2 phosphorylation in response to genotoxic stress in Candida albicans.Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cellsTRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.Chemotherapy induced DNA damage response: convergence of drugs and pathwaysPatient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathwaySerine/threonine phosphatases in the DNA damage response and cancer.APC as a mobile scaffold: regulation and function at the nucleus, centrosomes, and mitochondria.Human JC virus small tumour antigen inhibits nucleotide excision repair and sensitises cells to DNA-damaging agents.Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration.Response to DNA damage: why do we need to focus on protein phosphatases?PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines.Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'.Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress.
P2860
Q21263027-1FB8121B-2D1D-4014-8E84-DF1849D8E8B5Q24299264-FDA50647-D155-4624-B13A-96ED9D5A2B8DQ24301492-DABBA0BE-2943-42A1-955A-D7788A3A3CC6Q26827954-8CAA5E46-83DD-4369-AA01-E155A3FE7DECQ33529360-4C48DBD5-2C10-4BD7-B1C6-D13B091303AAQ33894393-7EA3A508-8AD9-4F25-AD23-9F649C67E727Q34007468-89AF0BA6-4179-4F56-BA38-72A138E5AD03Q34161464-6DA628F6-AB92-4244-986D-D55F4243BE1CQ34198570-1A84AF53-84E3-4F96-A7AC-4B27BB0030DAQ34414504-1E71E6B5-3E9A-440C-8B54-E2A41AB4570CQ34472318-E1D655B1-EC40-46B9-BAEE-A5B7AFAB4B20Q34565133-6614F882-34FB-4113-A1D8-4BBC83DFFD32Q35145726-EFA38808-CCA5-4874-9BBC-C5CEF42663C8Q35222474-180E4F00-A349-415F-AB9A-73A8F98026C4Q35745476-10A333CF-BC76-4C17-A3BA-6CD7CE464D2EQ36419741-8A0BA8B3-D597-4F59-B1FC-908F5288C27FQ36901484-22F859D7-9842-425D-8B33-96DD50DD0C53Q36974742-3E44FF8E-1F32-4D9C-85DB-62FEF836222AQ37788536-4198B3B8-E52B-43C1-8850-389C7C789B8EQ37967625-5571EAD9-5B62-499F-B800-6F5AFE4BD1D1Q38903158-F185A593-8115-435D-8BB7-4E2AEA86B727Q40672836-BFC32F2E-185A-4D9A-9055-273031660915Q43101429-5E959D5A-D92A-4B50-BC6A-AB031D572294Q47177215-7289833C-7EF4-495D-ABCF-AF88F10D67C7Q47420946-40C31121-8362-496C-9B7C-EE5B5A812D69Q49380019-4FB848F6-EC94-4B9A-BA69-3FF2C925C313
P2860
Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Protein phosphatase 2A-depende ...... induced by replication stress
@ast
Protein phosphatase 2A-depende ...... induced by replication stress
@en
type
label
Protein phosphatase 2A-depende ...... induced by replication stress
@ast
Protein phosphatase 2A-depende ...... induced by replication stress
@en
prefLabel
Protein phosphatase 2A-depende ...... induced by replication stress
@ast
Protein phosphatase 2A-depende ...... induced by replication stress
@en
P2093
P2860
P356
P1476
Protein phosphatase 2A-depende ...... induced by replication stress
@en
P2093
Junjie Feng
Sally Kornbluth
Sheila Yong
Timothy Wakeman
Xiao-Fan Wang
Xiaohua Wu
P2860
P304
P356
10.1128/MCB.00191-09
P407
P577
2009-08-24T00:00:00Z