Serine/threonine phosphatases in the DNA damage response and cancer.
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TGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyBRCT domains: A little more than kin, and less than kindDephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.Hyperforin inhibits Akt1 kinase activity and promotes caspase-mediated apoptosis involving Bad and Noxa activation in human myeloid tumor cells.The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exitDifferential effects of nitrostyrene derivatives on myelopoiesis involve regulation of C/EBPα and p38MAPK activity.Greatwall and Polo-like kinase 1 coordinate to promote checkpoint recoveryOverexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins.The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicityRegulation of polo-like kinase 1 by DNA damage and PP2A/B55αDeficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancerWorking hard for recovery: mitotic kinases in the DNA damage checkpointCompensation, crosstalk and sequestering: the currency of checkpoints in cancerNovel Ser/Thr protein phosphatases in cell death regulationBinding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activityEKPD: a hierarchical database of eukaryotic protein kinases and protein phosphatases.Defying DNA double-strand break-induced death during prophase I meiosis by temporal TAp63α phosphorylation regulation in developing mouse oocytes.DNA double-strand break - induced pro-survival signaling.Inflammation-induced radioresistance is mediated by ROS-dependent inactivation of protein phosphatase 1 in non-small cell lung cancer cells.ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation.A polymer-(tandem drugs) conjugate for enhanced cancer treatment.RAD001 (everolimus) induces dose-dependent changes to cell cycle regulation and modifies the cell cycle response to vincristine.A novel role for greatwall kinase in recovery from DNA damage.A role for protein phosphatase 4 in regulating non-homologous end-joining.Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining.Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B.Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide-Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells.HDAC inhibitor sodium butyrate sensitizes E1A+Ras-transformed cells to DNA damaging agents by facilitating formation and persistence of γH2AX foci.Expression of DNA doublestrand repair proteins in oral leukoplakia and the risk of malignant transformation.Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling
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Serine/threonine phosphatases in the DNA damage response and cancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 September 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Serine/threonine phosphatases in the DNA damage response and cancer.
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Serine/threonine phosphatases in the DNA damage response and cancer.
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type
label
Serine/threonine phosphatases in the DNA damage response and cancer.
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Serine/threonine phosphatases in the DNA damage response and cancer.
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prefLabel
Serine/threonine phosphatases in the DNA damage response and cancer.
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Serine/threonine phosphatases in the DNA damage response and cancer.
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P2860
P356
P1433
P1476
Serine/threonine phosphatases in the DNA damage response and cancer.
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P2093
P2860
P2888
P304
P356
10.1038/ONC.2010.371
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P577
2010-09-13T00:00:00Z