Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus.
about
Trans-dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the cis-dimerization interface.Mouse models for blistering skin disorders.Superficial dsg2 expression limits epidermal blister formation mediated by pemphigus foliaceus antibodies and exfoliative toxins.The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Autoimmunity to desmocollin 3 in pemphigus vulgaris.Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion.Pemphigus vulgaris autoantibody profiling by proteomic technique.A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype.Loss of Desmocollin 3 in skin tumor development and progressionThe extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesisPeptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blisteringMultiplexed autoantigen microarrays identify HLA as a key driver of anti-desmoglein and -non-desmoglein reactivities in pemphigus.Desmosomes: adhesive strength and signalling in health and disease.The pathogenic role of autoantibodies in pemphigus vulgaris.Desmosomal genodermatoses.Pemphigus autoimmunity: hypotheses and realities.Desmosomes and extradesmosomal adhesive signaling contacts in pemphigus.150(th) anniversary series: Desmosomes and autoimmune disease, perspective of dynamic desmosome remodeling and its impairments in pemphigus.Genetics of human isolated hereditary hair loss disorders.E-cadherin and Src associate with extradesmosomal Dsg3 and modulate desmosome assembly and adhesion.Loss of Desmoglein 2 Contributes to the Pathogenesis of Crohn's Disease.Pathophysiology of the Desmo-Adhesome.Desmoglein 2 compensates for desmoglein 3 but does not control cell adhesion via regulation of p38 mitogen-activated protein kinase in keratinocytes.Protective endogenous cyclic adenosine 5'-monophosphate signaling triggered by pemphigus autoantibodies.Actin reorganization contributes to loss of cell adhesion in pemphigus vulgaris.Experimental human cell and tissue models of pemphigus.Current concepts of pemphigus with a deep insight into its molecular aspects.IgG autoantibodies against desmocollin 3 in pemphigus sera induce loss of keratinocyte adhesion.iTRAQ-based proteomic profiling reveals different protein expression between normal skin and hypertrophic scar tissue.Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus.Recalcitrant pemphigus herpetiformis with high titer of immunoglobulin G antibody to desmoglein 1 and positive IgG antibody to desmocollin 3, elevating thymus and activation-regulated chemokine.Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus.Pemphigus-A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms.Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus.Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus.Non-Desmoglein Antibodies in Patients With Pemphigus Vulgaris.Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal MiceThe Evolving Story of Autoantibodies in Pemphigus Vulgaris: Development of the "Super Compensation Hypothesis"
P2860
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P2860
Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@ast
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@en
type
label
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@ast
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@en
prefLabel
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@ast
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@en
P2093
P2860
P356
P1476
Desmocollin 3-mediated binding ...... and is impaired in pemphigus.
@en
P2093
Athina Efthymiadis
Christian Rankl
Detlev Drenckhahn
Peter Hinterdorfer
Rüdiger Eming
Thomas Müller
Volker Spindler
Wolfgang-Moritz Heupel
P2860
P304
30556-30564
P356
10.1074/JBC.M109.024810
P407
P577
2009-08-28T00:00:00Z