Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer.
about
Clinical indications for thrombopoietin and thrombopoietin-receptor agonistsCytokines and hematopoietic stem cell mobilizationSelective enhancement of thrombopoietic activity of PEGylated interleukin 6 by a simple procedure using a reversible amino-protective reagent.Enhanced retention of in vitro functional activity of platelets from recombinant human thrombopoietin-treated patients following long-term cryopreservation with a platelet-preserving solution (ThromboSol) and 2% DMSO.Platelet growth factors: potential impact on transfusion medicine.Endogenous thrombopoietin serum levels during multicycle chemotherapy.Immunogenicity of thrombopoietin mimetic peptide GW395058 in BALB/c mice and New Zealand white rabbits: evaluation of the potential for thrombopoietin neutralizing antibody production in man.Thrombopoietin.Pharmacokinetics, pharmacodynamics, and safety of administering pegylated recombinant megakaryocyte growth and development factor to newborn rhesus monkeys.Phase 1 study of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients after autologous peripheral blood progenitor cell (PBPC) transplantation.Dose-response relationship of megakaryocyte progenitors from the bone marrow of thrombocytopenic and non-thrombocytopenic neonates to recombinant thrombopoietin.The pharmacokinetics and pharmacodynamics of GW395058, a peptide agonist of the thrombopoietin receptor, in the dog, a large-animal model of chemotherapy-induced thrombocytopenia.Effects of Mpl ligands on platelet production and function in nonhuman primates.Endogenous TPO (eTPO) levels in health and disease: possible clues for therapeutic intervention.Opportunities for the use of thrombopoietic growth factors.Recombinant human thrombopoietin (rhTPO) after autologous bone marrow transplantation: a phase I pharmacokinetic and pharmacodynamic study.Failing to live up to the fanfare? A personal perspective on obstacles to the clinical development of thrombopoietic agents.Serum levels of endogenous thrombopoietin and granulocyte-colony stimulating factor in patients with acute or lymphoma type adult T-cell leukemia during multicycle chemotherapy.Thrombopoietin as a drug: biologic expectations, clinical realities, and future directions.New TPO treatment schedules of increased safety and efficacy: pre-clinical validation of a thrombopoiesis simulation model.Endogenous thrombopoietin levels during the clinical management of acute myeloid leukaemia.Review article: thrombocytopenia in chronic liver disease and pharmacologic treatment options.A rationally designed agonist antibody fragment that functionally mimics thrombopoietinThe incidence and impact of thrombocytopenia in myelodysplastic syndromes.Review article: pharmacological approaches for the treatment of thrombocytopenia in patients with chronic liver disease and hepatitis C infection.New drugs for familiar therapeutic targets: thrombopoietin receptor agonists and immune thrombocytopenic purpura.AKR-501 (YM477) a novel orally-active thrombopoietin receptor agonist.New advances in the treatment of adult chronic immune thrombocytopenic purpura: role of thrombopoietin receptor-stimulating agents.Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside.Thrombocytopenia in patients with myelodysplastic syndromes.Toxicities of the thrombopoietic growth factorsEltrombopag--a novel approach for the treatment of chronic immune thrombocytopenic purpura: review and safety considerations.The biology of thrombopoietin and thrombopoietin receptor agonists.Diagnosis and management of autoimmune cytopenias in childhood.Thrombopoietin from beginning to end.Pharmacodynamic model for chemoradiotherapy-induced thrombocytopenia in mice.Eltrombopag for treatment of thrombocytopenia-associated disorders.Development of Romiplostim for Treatment of Primary Immune Thrombocytopenia From a Pharmacokinetic and Pharmacodynamic Perspective.Thrombocytopenia-Platelet Support or Growth Factors?Thrombocytopenia in Patients with Chronic Hepatitis C Virus Infection
P2860
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P2860
Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@ast
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@en
type
label
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@ast
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@en
prefLabel
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@ast
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@en
P2093
P1476
Stimulation of megakaryocyte a ...... ietin in patients with cancer.
@en
P2093
Benjamin RS
Broxmeyer HE
Bueso-Ramos C
Hellmann SD
Hittelman WN
Johnston DA
Johnston T
P304
P356
10.7326/0003-4819-126-9-199705010-00001
P407
P577
1997-05-01T00:00:00Z