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The magic of bicelles lights up membrane protein structureThe p7 protein of hepatitis C virus forms structurally plastic, minimalist ion channelsNMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C VirusThree-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl- sn -glycero-3-phosphocholine by Solution Nuclear Magnetic ResonanceStructure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion releaseCoupling neutron reflectivity with cell-free protein synthesis to probe membrane protein structure in supported bilayers.Single tryptophan and tyrosine comparisons in the N-terminal and C-terminal interface regions of transmembrane GWALP peptidesSecondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesNanodiscs versus macrodiscs for NMR of membrane proteins.1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples.Relating structure and function of viral membrane-spanning miniproteinsComputational modeling of the p7 monomer from HCV and its interaction with small molecule drugsComparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1.Hepatitis C virus p7: molecular function and importance in hepatitis C virus life cycle and potential antiviral target.Viruses as modulators of mitochondrial functions.Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy."Too little, too late?" Will inhibitors of the hepatitis C virus p7 ion channel ever be used in the clinic?Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors.Patch formation of a viral channel forming protein within a lipid membrane--Vpu of HIV-1.Two different conformations in hepatitis C virus p7 protein account for proton transport and dye release.Tyrosine replacing tryptophan as an anchor in GWALP peptides.The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein.Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses.Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7.Assembling an ion channel: ORF 3a from SARS-CoV
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
NMR studies of p7 protein from hepatitis C virus
@ast
NMR studies of p7 protein from hepatitis C virus
@en
type
label
NMR studies of p7 protein from hepatitis C virus
@ast
NMR studies of p7 protein from hepatitis C virus
@en
prefLabel
NMR studies of p7 protein from hepatitis C virus
@ast
NMR studies of p7 protein from hepatitis C virus
@en
P2860
P1476
NMR studies of p7 protein from hepatitis C virus
@en
P2093
Gabriel A Cook
Stanley J Opella
P2860
P2888
P304
P356
10.1007/S00249-009-0533-Y
P577
2009-09-02T00:00:00Z