Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.
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Emerging Roles of Viroporins Encoded by DNA Viruses: Novel Targets for Antivirals?Structural and Functional Properties of the Hepatitis C Virus p7 ViroporinViral Membrane Channels: Role and Function in the Virus Life CycleThe p7 protein of hepatitis C virus forms structurally plastic, minimalist ion channelsUnusual architecture of the p7 channel from hepatitis C virusStructure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion releaseIn depth analysis on the binding sites of adamantane derivatives in HCV (hepatitis C virus) p7 channel based on the NMR structureExploring Strong Interactions in Proteins with Quantum Chemistry and Examples of Their Applications in Drug DesignHigh-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesNS2 is dispensable for efficient assembly of hepatitis C virus-like particles in a bipartite trans-encapsidation system.Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugsHepatitis E virus ORF3 is a functional ion channel required for release of infectious particles"Too little, too late?" Will inhibitors of the hepatitis C virus p7 ion channel ever be used in the clinic?The Molecular Switch of Telomere Phages: High Binding Specificity of the PY54 Cro Lytic Repressor to a Single Operator Site.Two different conformations in hepatitis C virus p7 protein account for proton transport and dye release.Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride.Exploiting adamantane as a versatile organic tecton: multicomponent catalytic cascade reactions.Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5
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P2860
Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.
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2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en-gb
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@nl
type
label
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en-gb
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@nl
prefLabel
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en-gb
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@nl
P2093
P2860
P50
P356
P1433
P1476
Resistance mutations define sp ...... atitis C virus p7 ion channel.
@en
P2093
Ann L Wozniak
Elizabeth Atkins
Joseph Thompson
Mark Verow
Matthew J Bentham
Steven A Weinman
P2860
P356
10.1002/HEP.24371
P407
P577
2011-07-01T00:00:00Z