Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
about
Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHDFacioscapulohumeral dystrophy: incomplete suppression of a retrotransposed geneA muscle stem cell for every muscle: variability of satellite cell biology among different muscle groupsTransgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD)Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophyGenetics. Exposing a DUX tale.Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene.Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4.Human skeletal muscle xenograft as a new preclinical model for muscle disordersExpression, tandem repeat copy number variation and stability of four macrosatellite arrays in the human genome.A family history of DUX4: phylogenetic analysis of DUXA, B, C and Duxbl reveals the ancestral DUX gene.Testing the effects of FSHD candidate gene expression in vertebrate muscle development.TF-Cluster: a pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM)Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patternsDistinct epigenomic features in end-stage failing human heartsFacioscapulohumeral muscular dystrophy and DUX4: breaking the silence.Facioscapulohumeral muscular dystrophy as a model for epigenetic regulation and diseaseMuscle pathology grade for facioscapulohumeral muscular dystrophy biopsies.Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen.RNA interference inhibits DUX4-induced muscle toxicity in vivo: implications for a targeted FSHD therapy.Generation of isogenic D4Z4 contracted and noncontracted immortal muscle cell clones from a mosaic patient: a cellular model for FSHDConditional over-expression of PITX1 causes skeletal muscle dystrophy in mice.CRISPR/dCas9-mediated Transcriptional Inhibition Ameliorates the Epigenetic Dysregulation at D4Z4 and Represses DUX4-fl in FSH Muscular Dystrophy.Reevaluating measures of disease progression in facioscapulohumeral muscular dystrophyEstrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.Developments in RNA splicing and disease.In junk we trust: repetitive DNA, epigenetics and facioscapulohumeral muscular dystrophy.Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell culturesHigh-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity.Conservation and innovation in the DUX4-family gene network.Comprehensive comparative homeobox gene annotation in human and mouse.PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.Facioscapulohumeral dystrophy: Activating an early embryonic transcriptional program in human skeletal muscle.
P2860
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P2860
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@ast
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@en
type
label
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@ast
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@en
prefLabel
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@ast
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.
@en
P2860
P50
P1433
P1476
Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats
@en
P2093
Darko Bosnakovski
Randy S Daughters
P2860
P356
10.1371/JOURNAL.PONE.0007003
P407
P577
2009-09-16T00:00:00Z