Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.

Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.

Item
http://www.wikidata.org/entity/Q33504260
Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylaseThe ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibitionFragment-based discovery of novel thymidylate synthase leads by NMR screening and group epitope mapping.Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.The renal effects of the water-soluble, non-folylpolyglutamate synthetase-dependent thymidylate synthase inhibitor ZD9331 in mice.Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1)Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331A novel class of lipophilic quinazoline-based folic acid analogues: cytotoxic agents with a folate-independent locus.Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
P2860

Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.

Item
http://www.wikidata.org/entity/Q33504260
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@ast
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@en
type
label
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@ast
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@en
prefLabel
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@ast
Cellular pharmacology and in v ...... bitor of thymidylate synthase.
@en
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
Cellular pharmacology and in v ...... ibitor of thymidylate synthase
@en
P2093
P304
P31
P407
P433
P478
P577
P698