Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.

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Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.

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P2860

Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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Determinants of the activities ...... receptor-mediated endocytosis.

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P2093

I David Goldman

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Michele Visentin

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Rongbao Zhao

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P2860

Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption

Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibit

The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption

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The alpha folate receptor is highly activated in malignant pleural mesothelioma.

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Mechanisms of membrane transport of folates into cells and across epithelia.

Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma.

Molecular characterization of folate receptor 1 mutations delineates cerebral folate transport deficiency.

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Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.

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P2860

P2860

Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.

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P1476

P2093

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