AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
about
Diverse mechanisms of AKT pathway activation in human malignancyPI3K-independent AKT activation in cancers: a treasure trove for novel therapeuticsCancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domainMGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer casesMutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma.Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium.Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group.Personalized therapy in endometrial cancer: challenges and opportunities.Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing.The genomics and genetics of endometrial cancer.Application of Immunohistochemistry and Molecular Diagnostics to Clinically Relevant Problems in Endometrial Cancer Bojana Djordjevic, Shannon Westin, Russell R. BroaddusFive endometrial cancer risk loci identified through genome-wide association analysis.A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 BindingPersonalized care in uterine cancer.Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.Targeting the PI3-kinase/Akt/mTOR signaling pathway.Targeting the PI3K signaling pathway in cancer therapy.AKT Inhibition in Solid Tumors With AKT1 Mutations.AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.
P2860
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P2860
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@ast
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@en
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@nl
type
label
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@ast
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@en
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@nl
prefLabel
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@ast
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@en
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@nl
P2093
P1433
P1476
AKT1 pleckstrin homology domain E17K activating mutation in endometrial carcinoma.
@en
P2093
Bruria Shalmon
Eddie Fridman
Gideon Rechavi
Iris Barshack
Jacob Korach
Yoram Cohen
P356
10.1016/J.YGYNO.2009.09.038
P407
P577
2009-10-22T00:00:00Z