Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire. - Wikidata - awgldk - TriplyDB

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.

http://www.wikidata.org/entity/Q33513799

about

Fundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymes Therapeutic antibodies, vaccines and antibodyomes Deep sequencing in library selection projects: what insight does it bring?The analysis of clonal expansions in normal and autoimmune B cell repertoires The evolution within us Opportunities for functional selectivity in GPCR antibodies Glioblastoma cancer stem cells: Biomarker and therapeutic advances Next generation sequencing: new tools in immunology and hematology Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies High-Throughput Sequencing-Based Immune Repertoire Study during Infectious Disease Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting Revealing individual signatures of human T cell CDR3 sequence repertoires with Kidera Factors A Drug-Centric View of Drug Development: How Drugs Spread from Disease to Disease Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA Dimeric FcγR Ectodomains as Probes of the Fc Receptor Function of Anti-Influenza Virus IgG.Twenty years of combinatorial antibody libraries, but how well do they mimic the immunoglobulin repertoire?Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.Sequencing antibody repertoires: the next generation.Antibodies against non-immunizing antigens derived from a large immune scFv library 454 antibody sequencing - error characterization and correction.Immunological memory to hyperphosphorylated tau in asymptomatic individuals.The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing.Mining human antibody repertoires.Proteomic identification of monoclonal antibodies from serum By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection CNS Aquaporin-4-specific B cells connect with multiple B-cell compartments in neuromyelitis optica spectrum disorder.B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis.A Haystack Heuristic for Autoimmune Disease Biomarker Discovery Using Next-Gen Immune Repertoire Sequencing Data The promise and challenge of high-throughput sequencing of the antibody repertoire.Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex systems.High-resolution description of antibody heavy-chain repertoires in humans.Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries.Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM Repertoires Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations.Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing.

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Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.

http://www.wikidata.org/entity/Q33513799

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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Precise determination of the d ...... man immunoglobulin repertoire.

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PNAS.0909775106

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Precise determination of the d ...... man immunoglobulin repertoire.

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P2093

Arvind Rajpal

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Dilduz Telman

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Gabriella Huerta

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Gautam R Mehta

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Giles M R Day

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Irene Ni

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Jacob Glanville

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Jan Berka

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Jaume Pons

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Li Mei

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P2860

Genome sequencing in microfabricated high-density picolitre reactors

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus

The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line

Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods

Somatic generation of antibody diversity

Predicting protein structure using hidden Markov models.

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.

By-passing immunization. Human antibodies from V-gene libraries displayed on phage.

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides.

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20216-20221

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10.1073/PNAS.0909775106

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48

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106

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2009-10-29T00:00:00Z

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19875695

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