Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.
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Pregnane X receptor as a target for treatment of inflammatory bowel disordersTranscriptional regulators of claudins in epithelial tight junctionsLoss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiationOrganic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubuleGeneration of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated diseaseGenetics and pathogenesis of inflammatory bowel diseaseSrc tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alphaPediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsModification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.Prevention of diabetes-promoted colorectal cancer by (n-3) polyunsaturated fatty acids and (n-3) PUFA mimetic.Human Intestinal Barrier Function in Health and DiseaseVertebrate intestinal endoderm development.Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.ePIANNO: ePIgenomics ANNOtation tool.HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation.Prevention of chronic experimental colitis induced by dextran sulphate sodium (DSS) in mice treated with FR91.Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Identification of five novel modifier loci of Apc(Min) harbored in the BXH14 recombinant inbred strain.HNF4α: a new biomarker in colon cancer?Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascadesHepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters.Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics.Micro-RNAs in inflammatory diseases and as a link between inflammation and cancer.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networksJAM-related proteins in mucosal homeostasis and inflammationMPA Modulates Tight Junctions' Permeability via Midkine/PI3K Pathway in Caco-2 Cells: A Possible Mechanism of Leak-Flux Diarrhea in Organ Transplanted Patients.Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.Hepatocyte nuclear factor 4α suppresses the aggravation of colon carcinoma.Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease.An Overview of Inflammatory Bowel Disease: General Consideration and Genetic Screening Approach in Diagnosis of Early Onset Subsets.Layered defense: how mucus and tight junctions seal the intestinal barrier.Perspectives on tight junction research.Hepatocyte Nuclear Factor 4α Regulates the Expression of Intestinal Epithelial Na(+)/H(+) Exchanger Isoform-3 (NHE3).
P2860
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P2860
Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@ast
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@en
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@nl
type
label
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@ast
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@en
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@nl
prefLabel
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@ast
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@en
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@nl
P2093
P2860
P1433
P1476
Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.
@en
P2093
Andrée-Anne Dupuis
Elena F Verdu
Emile Lévy
Emma E Furth
Ernest G Seidman
Fernand-Pierre Gendron
François Boudreau
Jean-Philippe Babeu
Mathieu Darsigny
P2860
P356
10.1371/JOURNAL.PONE.0007609
P407
P577
2009-10-29T00:00:00Z