Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice. - Wikidata - awgldk - TriplyDB

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.

http://www.wikidata.org/entity/Q33515575

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Pregnane X receptor as a target for treatment of inflammatory bowel disorders Transcriptional regulators of claudins in epithelial tight junctions Loss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease Genetics and pathogenesis of inflammatory bowel disease Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.Nuclear receptor HNF4α binding sequences are widespread in Alu repeats Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.Prevention of diabetes-promoted colorectal cancer by (n-3) polyunsaturated fatty acids and (n-3) PUFA mimetic.Human Intestinal Barrier Function in Health and Disease Vertebrate intestinal endoderm development.Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.ePIANNO: ePIgenomics ANNOtation tool.HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation.Prevention of chronic experimental colitis induced by dextran sulphate sodium (DSS) in mice treated with FR91.Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Identification of five novel modifier loci of Apc(Min) harbored in the BXH14 recombinant inbred strain.HNF4α: a new biomarker in colon cancer?Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascades Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters.Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics.Micro-RNAs in inflammatory diseases and as a link between inflammation and cancer.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks JAM-related proteins in mucosal homeostasis and inflammation MPA Modulates Tight Junctions' Permeability via Midkine/PI3K Pathway in Caco-2 Cells: A Possible Mechanism of Leak-Flux Diarrhea in Organ Transplanted Patients.Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.Hepatocyte nuclear factor 4α suppresses the aggravation of colon carcinoma.Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease.An Overview of Inflammatory Bowel Disease: General Consideration and Genetic Screening Approach in Diagnosis of Early Onset Subsets.Layered defense: how mucus and tight junctions seal the intestinal barrier.Perspectives on tight junction research.Hepatocyte Nuclear Factor 4α Regulates the Expression of Intestinal Epithelial Na(+)/H(+) Exchanger Isoform-3 (NHE3).

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P2860

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.

http://www.wikidata.org/entity/Q33515575

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

@wuu

name

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@ast

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@en

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@nl

type

label

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@ast

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@en

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@nl

prefLabel

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@ast

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@en

Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@nl

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JOURNAL.PONE.0007609

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Loss of hepatocyte-nuclear-fac ...... mmatory bowel disease in mice.

@en

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Andrée-Anne Dupuis

http://www.w3.org/2001/XMLSchema#string

Elena F Verdu

http://www.w3.org/2001/XMLSchema#string

Emile Lévy

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Emma E Furth

http://www.w3.org/2001/XMLSchema#string

Ernest G Seidman

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Fernand-Pierre Gendron

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François Boudreau

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Jean-Philippe Babeu

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Mathieu Darsigny

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P2860

Functional variants of OCTN cation transporter genes are associated with Crohn disease

HNF-4alpha: from MODY to late-onset type 2 diabetes

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

Unravelling the pathogenesis of inflammatory bowel disease

Characterization of variability in large-scale gene expression data: implications for study design.

Regulation of intestinal epithelial cell apoptosis and the pathogenesis of inflammatory bowel disorders.

Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage.

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

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4

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2009-10-29T00:00:00Z

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38075522

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19898610

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inflammatory bowel diseases

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2764139

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