Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha
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HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cellsThe nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilliExpression of HNF4alpha in the human and rat choroid plexus: implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrierImproved conditional expression systems resulting in physiological level of HNF4alpha expression confirm HNF4alpha induced apoptosis in the pancreatic beta-cell line INS-1.Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors.Claudins and the modulation of tight junction permeability.A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.The possible role of ribosomal protein S6 kinase 4 in the senescence of endothelial progenitor cells in diabetes mellitusDysregulated in vitro hematopoiesis, radiosensitivity, proliferation, and osteoblastogenesis with marrow from SAMP6 mice.Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.Regulation of hepatocyte identity and quiescence.Cardenolide glycosides from the seeds of Digitalis purpurea exhibit carcinoma-specific cytotoxicity toward renal adenocarcinoma and hepatocellular carcinoma cells.Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene.
P2860
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P2860
Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2005
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im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
name
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@ast
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@en
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@nl
type
label
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@ast
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@en
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@nl
prefLabel
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@ast
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@en
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@nl
P2093
P1476
Activation of p21CIP1/WAF1 gen ...... patocyte nuclear factor-4alpha
@en
P2093
Hideki Chiba
Hiroko Noguchi
Makoto Osanai
Naoyuki Sakai
Norimasa Sawada
Seiro Satohisa
Taisei Itoh
Takashi Kojima
P356
10.1016/J.YEXCR.2004.08.014
P407
P577
2005-01-01T00:00:00Z