Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols.
about
Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malariaExpanding the Antimalarial Drug Arsenal-Now, But How?Mass administration of the antimalarial drug mefloquine to Guantánamo detainees: a critical analysis.A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice.Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration.Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models.Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum.Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.4-Chloro-2,5-dimethyl-quinoline.Differences in anti-malarial activity of 4-aminoalcohol quinoline enantiomers and investigation of the presumed underlying mechanism of action
P2860
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P2860
Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Anti-malarial activity of a no ...... eneration quinoline methanols.
@ast
Anti-malarial activity of a no ...... eneration quinoline methanols.
@en
Anti-malarial activity of a no ...... eneration quinoline methanols.
@nl
type
label
Anti-malarial activity of a no ...... eneration quinoline methanols.
@ast
Anti-malarial activity of a no ...... eneration quinoline methanols.
@en
Anti-malarial activity of a no ...... eneration quinoline methanols.
@nl
prefLabel
Anti-malarial activity of a no ...... eneration quinoline methanols.
@ast
Anti-malarial activity of a no ...... eneration quinoline methanols.
@en
Anti-malarial activity of a no ...... eneration quinoline methanols.
@nl
P2093
P2860
P356
P1433
P1476
Anti-malarial activity of a no ...... eneration quinoline methanols.
@en
P2093
Charlotte Lanteri
Diana Caridha
Duane Goodine
Erin Milner
Geoffrey Stuart Dow
Jason Sousa
Jayendra Bhonsle
Jose Cobar
Lucia Gerena
Norma Roncal
P2860
P2888
P356
10.1186/1475-2875-9-51
P50
P577
2010-02-11T00:00:00Z
P5875
P6179
1048889293