Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.

Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.

Item
http://www.wikidata.org/entity/Q33526131
Recent advances in malaria drug discoveryAnti-malarial activity of a non-piperidine library of next-generation quinoline methanols.An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cellsExpanding the Antimalarial Drug Arsenal-Now, But How?A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice.A small-fish model for behavioral-toxicological screening of new antimalarial drugs: a comparison between erythro- and threo-mefloquine.The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models.Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum.Recent advances in research of natural and synthetic bioactive quinolines.Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.Novel brominated quinoline and pyrimidoquinoline derivatives as potential cytotoxic agents with synergistic effects of γ-radiation.
P2860

Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.

Item
http://www.wikidata.org/entity/Q33526131
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure-activity relationshi ...... ains of Plasmodium falciparum.
@ast
Structure-activity relationshi ...... ains of Plasmodium falciparum.
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Structure-activity relationshi ...... ains of Plasmodium falciparum.
@nl
type
label
Structure-activity relationshi ...... ains of Plasmodium falciparum.
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Structure-activity relationshi ...... ains of Plasmodium falciparum.
@en
Structure-activity relationshi ...... ains of Plasmodium falciparum.
@nl
prefLabel
Structure-activity relationshi ...... ains of Plasmodium falciparum.
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Structure-activity relationshi ...... ains of Plasmodium falciparum.
@en
Structure-activity relationshi ...... ains of Plasmodium falciparum.
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Structure-activity relationshi ...... ains of Plasmodium falciparum.
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P2093
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P356
10.1016/J.BMCL.2010.01.001
P407
P433
P478
P50
P577
P698
P921