Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
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Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cellsDifferences between the catalytic properties of recombinant human PC2 and endogenous rat PC2Processing of prothyrotropin-releasing hormone by the family of prohormone convertasesPost-translational processing of progastrin: inhibition of cleavage, phosphorylation and sulphation by brefeldin AFurin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteinsGene organization and alternative splicing of human prohormone convertase PC8PC8 [corrected], a new member of the convertase familyStructural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 proteaseRegulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputsIsolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptidesCART in the regulation of appetite and energy homeostasisSubtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve headRegulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoterNeuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elementsProcessing of proSAAS in neuroendocrine cell linesMechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not foldingDifferential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: implications for understanding the "switch" to opiate addictMutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1)Selective expression of the proprotein convertases furin, pc5, and pc7 in proliferating vascular smooth muscle cells of the rat aorta in vitroImmunocytochemical localization of the prohormone convertases PC1 and PC2 in rat prolactin cellsImmunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of pro-neurotensin in rat brainProinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3A model for the structure of the P domains in the subtilisin-like prohormone convertases.Processing of proenkephalin-A in bovine chromaffin cells. Identification of natural derived fragments by N-terminal sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry.The cDNA structure of the porcine pro-hormone convertase PC2 and the comparative processing by PC1 and PC2 of the N-terminal glycopeptide segment of porcine POMC.Is the defect in pro-hormone processing in Type 2 diabetes mellitus restricted to the beta cell?Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.cDNA sequence of a Drosophila melanogaster gene, Dfur1, encoding a protein structurally related to the subtilisin-like proprotein processing enzyme furin.Dynamic changes in proprotein convertase 2 activity in cortical neurons after ischemia/reperfusion and oxygen-glucose deprivationGeneration of structural and functional diversity in furin-like proteins in Drosophila melanogaster by alternative splicing of the Dfur1 geneBiochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary.Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity.Proprotein convertases in amphioxus: predicted structure and expression of proteases SPC2 and SPC3Proprotein convertase 1/3 (PC1/3) in the rat alveolar macrophage cell line NR8383: localization, trafficking and effects on cytokine secretion.The Kex2p proregion is essential for the biosynthesis of an active enzyme and requires a C-terminal basic residue for its function.Proinsulin endoproteolysis confers enhanced targeting of processed insulin to the regulated secretory pathwayProcessing of proopiomelanocortin by insulin secretory granule proinsulin processing endopeptidases.
P2860
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P2860
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Cloning and primary sequence o ...... and pituitary compared to PC2.
@ast
Cloning and primary sequence o ...... and pituitary compared to PC2.
@en
Cloning and primary sequence o ...... and pituitary compared to PC2.
@nl
type
label
Cloning and primary sequence o ...... and pituitary compared to PC2.
@ast
Cloning and primary sequence o ...... and pituitary compared to PC2.
@en
Cloning and primary sequence o ...... and pituitary compared to PC2.
@nl
prefLabel
Cloning and primary sequence o ...... and pituitary compared to PC2.
@ast
Cloning and primary sequence o ...... and pituitary compared to PC2.
@en
Cloning and primary sequence o ...... and pituitary compared to PC2.
@nl
P2093
P356
P1476
Cloning and primary sequence o ...... and pituitary compared to PC2.
@en
P2093
G Beaubien
M Chrétien
M G Mattei
M Marcinkiewicz
N G Seidah
S Benjannet
P304
P356
10.1210/MEND-5-1-111
P577
1991-01-01T00:00:00Z