Intracellular signalling: PDK1--a kinase at the hub of things.
about
DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositidesPotential role of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in insulin-stimulated glucose transporter 4 translocation in adipocytesVisualization of biochemical networks in living cellsRegulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/AktDNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survivalMechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinasePhosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivoThe PI3K-PDK1 connection: more than just a road to PKBPhosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinaseSerum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathwayFunctional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translationIdentification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKAModulation of Akt kinase activity by binding to Hsp90A comprehensive pathway map of epidermal growth factor receptor signalingThe Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiaeA 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAPAkt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylationRegulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation siteThe PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-CellsTyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signalingCharacterization of thyrotropin receptor antibody-induced signaling cascadesInsulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activityMammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeletonMembrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells.Modulation of cyclin D1 and its signaling components by the phorbol ester TPA and the tyrosine phosphatase inhibitor vanadate.Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner.Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation.3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinasesMaternal gene expression in Atlantic halibut (Hippoglossus hippoglossus L.) and its relation to egg quality.Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.Modulation of cellular apoptotic potential: contributions to oncogenesis.Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesisPDK1 regulates growth through Akt and S6K in Drosophila.PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways.The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1.The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation
P2860
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P2860
Intracellular signalling: PDK1--a kinase at the hub of things.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Intracellular signalling: PDK1--a kinase at the hub of things.
@ast
Intracellular signalling: PDK1--a kinase at the hub of things.
@en
Intracellular signalling: PDK1--a kinase at the hub of things.
@nl
type
label
Intracellular signalling: PDK1--a kinase at the hub of things.
@ast
Intracellular signalling: PDK1--a kinase at the hub of things.
@en
Intracellular signalling: PDK1--a kinase at the hub of things.
@nl
prefLabel
Intracellular signalling: PDK1--a kinase at the hub of things.
@ast
Intracellular signalling: PDK1--a kinase at the hub of things.
@en
Intracellular signalling: PDK1--a kinase at the hub of things.
@nl
P2093
P1433
P1476
Intracellular signalling: PDK1--a kinase at the hub of things.
@en
P2093
P356
10.1016/S0960-9822(99)80058-X
P407
P577
1999-02-01T00:00:00Z