Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
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A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activityMucosal vaccination against encapsulated respiratory bacteria--new potentials for conjugate vaccines?Intranasal immunization with recombinant HA and mast cell activator C48/80 elicits protective immunity against 2009 pandemic H1N1 influenza in miceInduction of thymus-derived gammadelta T Cells by Escherichia coli enterotoxin b subunit in peritoneal cavities of miceIntranasal immunization of mice with inactivated virus and mast cell activator C48/80 elicits protective immunity against influenza H1 but not H5.Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxinsIntranasal delivery of cholera toxin induces th17-dominated T-cell response to bystander antigens.Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities.Cholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by type I and type II heat-labile enterotoxins.Secretory immunoglobulin A: from mucosal protection to vaccine development.Protective mucosal immunity to ocular herpes simplex virus type 1 infection in mice by using Escherichia coli heat-labile enterotoxin B subunit as an adjuvant.Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)Intranasal immunization with pneumococcal polysaccharide conjugate vaccines with nontoxic mutants of Escherichia coli heat-labile enterotoxins as adjuvants protects mice against invasive pneumococcal infections.Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells.Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum.Human infection with Ascaris lumbricoides is associated with suppression of the interleukin-2 response to recombinant cholera toxin B subunit following vaccination with the live oral cholera vaccine CVD 103-HgR.Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii.Escherichia coli heat-labile enterotoxin B subunit is a more potent mucosal adjuvant than its vlosely related homologue, the B subunit of cholera toxin.Escherichia coli enterotoxin B subunit triggers apoptosis of CD8(+) T cells by activating transcription factor c-myc.Nasal immunization with homogenate and peptide antigens induces protective immunity against Trichinella spiralisMutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functionsProbiotics and food-allergic diseases.Plasmid vectors encoding cholera toxin or the heat-labile enterotoxin from Escherichia coli are strong adjuvants for DNA vaccines.Different types of cell death induced by enterotoxins.Unexpected modulation of recall B and T cell responses after immunization with rotavirus-like particles in the presence of LT-R192G.Cholera toxin B: one subunit with many pharmaceutical applications.Expression and functional validation of heat-labile enterotoxin B (LTB) and cholera toxin B (CTB) subunits in transgenic rice (Oryza sativa).Production of secretory immunoglobulin A against Shiga toxin-binding subunits in mice by mucosal immunization.Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent.Cell clustering and delay/arrest in T-cell division implicate a novel mechanism of immune modulation by E. coli heat-labile enterotoxin B-subunits.Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cellsPeptide-based therapeutic vaccines for allergic and autoimmune diseases.Escherichia coli in postweaning diarrhea in pigs: an update on bacterial types, pathogenesis, and prevention strategies.Immunomodulation with enterotoxins for the generation of secretory immunity or tolerance: applications for oral infections.The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.Recombinant outer membrane protein F-B subunit of LT protein as a prophylactic measure against Pseudomonas aeruginosa burn infection in miceEnhancing DNA vaccine potency by modifying the properties of antigen-presenting cells.Transgenic tobacco expressed HPV16-L1 and LT-B combined immunization induces strong mucosal and systemic immune responses in mice.Cholera toxin B accelerates disease progression in lupus-prone mice by promoting lipid raft aggregation.
P2860
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P2860
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@ast
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@en
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@nl
type
label
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@ast
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@en
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@nl
prefLabel
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@ast
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@en
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@nl
P2093
P1433
P1476
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic.
@en
P2093
P304
P356
10.1016/S0167-5699(98)01397-8
P577
1999-02-01T00:00:00Z