Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.

Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.

Item
http://www.wikidata.org/entity/Q35689341
Cholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by type I and type II heat-labile enterotoxins.Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2.Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)LT-IIc, a new member of the type II heat-labile enterotoxin family encoded by an Escherichia coli strain obtained from a nonmammalian host.LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb.Immunogenicity and in vitro and in vivo protective effects of antibodies targeting a recombinant form of the Streptococcus mutans P1 surface protein.Distinctive immunomodulatory and inflammatory properties of the Escherichia coli type II heat-labile enterotoxin LT-IIa and its B pentamer following intradermal administration.TLR2-dependent modulation of dendritic cells by LT-IIa-B5, a novel mucosal adjuvant derived from a type II heat-labile enterotoxin.The Divergent CD8+ T Cell Adjuvant Properties of LT-IIb and LT-IIc, Two Type II Heat-Labile Enterotoxins, Are Conferred by Their Ganglioside-Binding B Subunits.Comparative Adjuvant Effects of Type II Heat-Labile Enterotoxins in Combination with Two Different Candidate Ricin Toxin Vaccine Antigens.Intranasal vaccines for protection against respiratory and systemic bacterial infections.Mucosal vaccines: novel strategies and applications for the control of pathogens and tumors at mucosal sites.Mucosal vaccination against bacterial respiratory infections.Type II heat-labile enterotoxins: structure, function, and immunomodulatory properties.Recent advances in nontoxic Escherichia coli heat-labile toxin and its derivative adjuvants.Enhancement of humoral immunity by the type II heat-labile enterotoxin LT-IIb is dependent upon IL-6 and neutrophils.
P2860

Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.

Item
http://www.wikidata.org/entity/Q35689341
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
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2006年论文
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name
Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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type
label
Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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prefLabel
Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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Mutants of type II heat-labile ...... are potent mucosal adjuvants.
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
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P1433
P1476
Mutants of type II heat-labile ...... y are potent mucosal adjuvants
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932