Predictive computational models of substrate binding by a nucleoside transporter.

Predictive computational models of substrate binding by a nucleoside transporter.

Item
http://www.wikidata.org/entity/Q33553416
Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma bruceiEvaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasisSymmetrical choline-derived dications display strong anti-kinetoplastid activity.The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomesTargeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategyFunctional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptakeGlycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery.Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein.9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance.
P2860

Predictive computational models of substrate binding by a nucleoside transporter.

Item
http://www.wikidata.org/entity/Q33553416
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Predictive computational models of substrate binding by a nucleoside transporter.
@ast
Predictive computational models of substrate binding by a nucleoside transporter.
@en
Predictive computational models of substrate binding by a nucleoside transporter.
@nl
type
label
Predictive computational models of substrate binding by a nucleoside transporter.
@ast
Predictive computational models of substrate binding by a nucleoside transporter.
@en
Predictive computational models of substrate binding by a nucleoside transporter.
@nl
prefLabel
Predictive computational models of substrate binding by a nucleoside transporter.
@ast
Predictive computational models of substrate binding by a nucleoside transporter.
@en
Predictive computational models of substrate binding by a nucleoside transporter.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Predictive computational models of substrate binding by a nucleoside transporter.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932