Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition. - Wikidata - awgldk - TriplyDB

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

http://www.wikidata.org/entity/Q33553507

about

P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation DNA damage control: regulation and functions of checkpoint kinase 1 Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?Roles of Chk1 in cell biology and cancer therapy Cell cycle-dependent localization of CHK2 at centrosomes during mitosis.PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.Ataxin-3 promotes genome integrity by stabilizing Chk1.Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2.Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage.Regulation of HuR by DNA Damage Response Kinases.Molecularly targeted therapies in non-small-cell lung cancer annual update 2014 3-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one (CHP) inhibits human ovarian cell proliferation by inducing apoptosis The fork and the kinase: a DNA replication tale from a CHK1 perspective.Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice.Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN)Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response.Beyond ATM: the protein kinase landscape of the DNA damage response.CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response.The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells.Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.Tumor-initiating cells contribute to radiation resistance in primary human renal clear cell carcinomas by activating the DNA damage checkpoint response.Caffeine stabilizes Cdc25 independently of Rad3 in Schizosaccharomyces pombe contributing to checkpoint override.Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearra The G2 checkpoint-a node-based molecular switch.Degrading Claspin away with Cdh1 and Cyclin A.Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.Preparing a cell for nuclear envelope breakdown: Spatio-temporal control of phosphorylation during mitotic entry.

P2860

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P2860

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

http://www.wikidata.org/entity/Q33553507

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@ast

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@en

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@nl

type

label

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@ast

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@en

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@nl

prefLabel

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@ast

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@en

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@nl

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JBC.C109.051540

P1433

Journal of Biological Chemistry

P1476

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

@en

P2093

Kousuke Kasahara

http://www.w3.org/2001/XMLSchema#string

Kunio Tsujimura

http://www.w3.org/2001/XMLSchema#string

Masaki Inagaki

http://www.w3.org/2001/XMLSchema#string

Masato Enomoto

http://www.w3.org/2001/XMLSchema#string

Tohru Kiyono

http://www.w3.org/2001/XMLSchema#string

Yasuko Tomono

http://www.w3.org/2001/XMLSchema#string

P2860

Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

Active cyclin B1-Cdk1 first appears on centrosomes in prophase

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

Checkpoints: controls that ensure the order of cell cycle events

The DNA damage response: putting checkpoints in perspective

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

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2797192

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