Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
about
P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferationDNA damage control: regulation and functions of checkpoint kinase 1Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?Roles of Chk1 in cell biology and cancer therapyCell cycle-dependent localization of CHK2 at centrosomes during mitosis.PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.Ataxin-3 promotes genome integrity by stabilizing Chk1.Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2.Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage.Regulation of HuR by DNA Damage Response Kinases.Molecularly targeted therapies in non-small-cell lung cancer annual update 20143-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one (CHP) inhibits human ovarian cell proliferation by inducing apoptosisThe fork and the kinase: a DNA replication tale from a CHK1 perspective.Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy responseCytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice.Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viabilityProtein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN)Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response.Beyond ATM: the protein kinase landscape of the DNA damage response.CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response.The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells.Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.Tumor-initiating cells contribute to radiation resistance in primary human renal clear cell carcinomas by activating the DNA damage checkpoint response.Caffeine stabilizes Cdc25 independently of Rad3 in Schizosaccharomyces pombe contributing to checkpoint override.Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearraThe G2 checkpoint-a node-based molecular switch.Degrading Claspin away with Cdh1 and Cyclin A.Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.Preparing a cell for nuclear envelope breakdown: Spatio-temporal control of phosphorylation during mitotic entry.
P2860
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P2860
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@ast
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@en
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@nl
type
label
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@ast
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@en
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@nl
prefLabel
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@ast
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@en
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@nl
P2093
P2860
P356
P1476
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
@en
P2093
Kousuke Kasahara
Kunio Tsujimura
Masaki Inagaki
Masato Enomoto
Tohru Kiyono
Yasuko Tomono
P2860
P304
34223-34230
P356
10.1074/JBC.C109.051540
P407
P577
2009-10-16T00:00:00Z