Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
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Characterization of the human insulin-induced gene 2 (INSIG2) promoter: the role of Ets-binding motifsProtein malnutrition during pregnancy in C57BL/6J mice results in offspring with altered circadian physiology before obesitySirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsAkt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathwaysRegulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1Sterol Regulatory Element-Binding Proteins (SREBP) signallingTranscriptional control of hepatic lipid metabolism by SREBP and ChREBP.Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets.Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes.Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signalsAnalysis of transcription factor network underlying 3T3-L1 adipocyte differentiation.Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potentialPanhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy.Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expressionPhosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets.Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells.Fish oil alleviated high-fat diet-induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study.Freshwater Clam Extract Ameliorates Triglyceride and Cholesterol Metabolism through the Expression of Genes Involved in Hepatic Lipogenesis and Cholesterol Degradation in RatsA novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes.E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis.Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue.Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation.Endoplasmic reticulum stress and lipid dysregulation.Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis.A pathway approach to investigate the function and regulation of SREBPs.Time of day and nutrients in feeding govern daily expression rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liverPPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fastingActivated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses.The interplay between cell signalling and the mevalonate pathway in cancer.cAMP response element binding protein H mediates fenofibrate-induced suppression of hepatic lipogenesis.Taurine is a liver X receptor-α ligand and activates transcription of key genes in the reverse cholesterol transport without inducing hepatic lipogenesis.Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation.PAS kinase drives lipogenesis through SREBP-1 maturation.Effect of insulin analogues on 3t3-l1 adipogenesis and lipolysis.Membrane traffic research: challenges for the next decade.Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity.Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP-1 interaction with a specific SCD1 promoter element.Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption.Nutritional regulation of renal lipogenic factor expression in mice: comparison to regulation in the liver and skeletal muscle.
P2860
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P2860
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@ast
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@en
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein
@nl
type
label
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@ast
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@en
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein
@nl
prefLabel
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@ast
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@en
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein
@nl
P2093
P2860
P356
P1476
Insulin enhances the biogenesi ...... otein (SCAP).SREBP-1c complex.
@en
P2093
Chandrahasa R Yellaturu
Edwards A Park
Marshall B Elam
Rajendra Raghow
Xiong Deng
P2860
P304
31726-31734
P356
10.1074/JBC.M109.050914
P407
P577
2009-09-16T00:00:00Z