TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function. - Wikidata - awgldk - TriplyDB

TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function.

TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function.

http://www.wikidata.org/entity/Q33557334

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MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner Pseudokinases: update on their functions and evaluation as new drug targets.The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis MiR-506 suppresses proliferation of hepatoma cells through targeting YAP mRNA 3'UTR.Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease.YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients.Two-signal requirement for growth-promoting function of Yap in hepatocytes MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1.MicroRNA-212 inhibits hepatocellular carcinoma cell proliferation and induces apoptosis by targeting FOXA1.YAP is a critical oncogene in human cholangiocarcinoma Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells.FZD7 regulates BMSCs-mediated protection of CML cells.Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cells Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway.Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways.Cluster of differentiation 166 (CD166) regulated by phosphatidylinositide 3-Kinase (PI3K)/AKT signaling to exert its anti-apoptotic role via yes-associated protein (YAP) in liver cancer.G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway.12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.The regulation and function of YAP transcription co-activator.Going for broke: targeting the human cancer pseudokinome.Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology.Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer.ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.The hippo signaling pathway: implications for heart regeneration and disease.Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.FOXA1 defines cancer cell specificity.The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells.TRIB2 regulates normal and stress-induced thymocyte proliferation.Yes-associated protein: A novel molecular target for the diagnosis, treatment and prognosis of hepatocellular carcinoma.Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

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P2860

TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function.

http://www.wikidata.org/entity/Q33557334

description

2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

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2013年論文

@zh-mo

2013年論文

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2013年论文

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name

TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

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J.MOLCEL.2013.05.013

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TRIB2 acts downstream of Wnt/T ...... ulate YAP and C/EBPα function.

@en

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Brian C Lewis

http://www.w3.org/2001/XMLSchema#string

Hongkai Ji

http://www.w3.org/2001/XMLSchema#string

Jennifer L Cotton

http://www.w3.org/2001/XMLSchema#string

Joo-Seop Park

http://www.w3.org/2001/XMLSchema#string

Junhao Mao

http://www.w3.org/2001/XMLSchema#string

Mihir Rajurkar

http://www.w3.org/2001/XMLSchema#string

Qishi Fan

http://www.w3.org/2001/XMLSchema#string

P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

TEAD mediates YAP-dependent gene induction and growth control

The hippo signaling pathway in development and cancer

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

Pioneer transcription factors: establishing competence for gene expression

Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression

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211-225

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10.1016/J.MOLCEL.2013.05.013

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2

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23769673

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4007693

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