Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
about
Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerβ-Catenin Signaling and Roles in Liver Homeostasis, Injury, and TumorigenesisThe regulation of β-catenin activity and function in cancer: therapeutic opportunitiesThe correlation between poor prognosis and increased yes-associated protein 1 expression in keratin 19 expressing hepatocellular carcinomas and cholangiocarcinomas.Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanismCo-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liverA miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis.YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.YAP is a critical oncogene in human cholangiocarcinomaFAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling.Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location.Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in miceSIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma.Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer.Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse OriginYAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma.Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant β-catenin.Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans.YAP and 14-3-3γ are involved in HS-OA-induced growth inhibition of hepatocellular carcinoma cells: A novel mechanism for hydrogen sulfide releasing oleanolic acid.Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivoEmerging role of Hippo signalling pathway in bladder cancer.MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway.Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage.YAP/TAZ at the Roots of Cancer.Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective.Hepatostat: Liver regeneration and normal liver tissue maintenance.Ribosomopathy-like properties of murine and human cancers.Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups.Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice.Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade.Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growthYAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin.Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development.Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
P2860
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P2860
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@en
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@nl
type
label
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@en
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@nl
prefLabel
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@en
Activation of β-catenin and Ya ...... hepatocarcinogenesis in mice.
@nl
P2093
P2860
P1433
P1476
Activation of β-catenin and Ya ...... f hepatocarcinogenesis in mice
@en
P2093
Diego F Calvisi
Frank Dombrowski
Junyan Tao
Lijie Jiang
Luigi Terracciano
Matthias Evert
Sarangarajan Ranganathan
Satdarshan P S Monga
P2860
P304
P356
10.1053/J.GASTRO.2014.05.004
P407
P577
2014-05-14T00:00:00Z