Metabolism-guided design of short-acting calcium-sensing receptor antagonists. - Wikidata - awgldk - TriplyDB

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

http://www.wikidata.org/entity/Q33557940

about

Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone Calcilytics: antagonists of the calcium-sensing receptor for the treatment of osteoporosis.Metabolism-guided drug design

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P2860

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

http://www.wikidata.org/entity/Q33557940

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@ast

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@en

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@nl

type

label

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@ast

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@en

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@nl

prefLabel

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@ast

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@en

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@nl

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P1433

ACS Medicinal Chemistry Letters

P1476

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

@en

P2093

Amit S Kalgutkar

http://www.w3.org/2001/XMLSchema#string

Brendon Kapinos

http://www.w3.org/2001/XMLSchema#string

David A Price

http://www.w3.org/2001/XMLSchema#string

David R Healy

http://www.w3.org/2001/XMLSchema#string

Gayatri Balan

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Gwendolyn D Fate

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John F Sagal

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Jonathan N Bauman

http://www.w3.org/2001/XMLSchema#string

Keith A Riccardi

http://www.w3.org/2001/XMLSchema#string

Mei Li

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

Application of the National Osteoporosis Foundation Guidelines to postmenopausal women and men: the Framingham Osteoporosis Study

Calcilytic compounds: potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone.

Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.

Impact of OATP transporters on pharmacokinetics.

Potential new drug targets for osteoporosis.

Metabolites in safety testing (MIST): considerations of mechanisms of toxicity with dose, abundance, and duration of treatment.

Clinical update on teriparatide.

Antagonists of the calcium receptor. 2. Amino alcohol-based parathyroid hormone secretagogues.

P304

219-223

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scholarly article

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10.1021/ML100058W

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5

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1

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James A Southers

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2010-05-13T00:00:00Z

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24900198

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4007832

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