Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.
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Hypercalcaemic and hypocalcaemic conditions due to calcium-sensing receptor mutationsMinireview: Nutrient sensing by G protein-coupled receptorsKokumi substances, enhancers of basic tastes, induce responses in calcium-sensing receptor expressing taste cellsMetabolism-guided design of short-acting calcium-sensing receptor antagonists.Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormonePhysiology and pathophysiology of the calcium-sensing receptor in the kidneyUpdate in new anabolic therapies for osteoporosisMutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia.Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice.Novel calcium sensing receptor ligands: a patent survey.Calcilytics: antagonists of the calcium-sensing receptor for the treatment of osteoporosis.Extracellular calcium-sensing receptor: structural and functional features and association with diseases.Amino alcohol- (NPS-2143) and quinazolinone-derived calcilytics (ATF936 and AXT914) differentially mitigate excessive signalling of calcium-sensing receptor mutants causing Bartter syndrome Type 5 and autosomal dominant hypocalcemiaCalcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection.Pharmacodynamic model of parathyroid hormone modulation by a negative allosteric modulator of the calcium-sensing receptorNovel treatments for osteoporosis.Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators.New concepts in calcium-sensing receptor pharmacology and signallingUpdate on bone anabolics in osteoporosis treatment: rationale, current status, and perspectivesNew treatment modalities in osteoporosis.The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).The calcium-sensing receptor in normal physiology and pathophysiology: a review.Emerging and potential therapies for osteoporosis.PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor.Osteoporosis: now and the futureInterplay between CaSR and PTH1R signaling in skeletal development and osteoanabolism.Anabolic skeletal therapy for osteoporosis.Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cellsTowards a structural understanding of allosteric drugs at the human calcium-sensing receptorAllosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.Emerging pharmacologic therapies for osteoporosis.Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension.Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy.The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion.The osteoporosis revolution marches on.The role of the calcium-sensing receptor in bone biology and pathophysiologyDisorders of phosphate homeostasis and tissue mineralisation.FGF23 and syndromes of abnormal renal phosphate handlingGα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy.Bone biology and anabolic therapies for bone: current status and future prospects.
P2860
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P2860
Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@ast
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@en
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@nl
type
label
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@ast
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@en
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@nl
prefLabel
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@ast
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@en
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@nl
P2093
P2860
P356
P1476
Antagonizing the parathyroid c ...... formation in osteopenic rats.
@en
P2093
Bhatnagar PK
Callahan JF
P2860
P304
P356
10.1172/JCI9038
P407
P577
2000-06-01T00:00:00Z