Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growthInsights into Chemoresistance of Prostate CancerStability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineagePDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascadeMitochondria as a source and target of lipid peroxidation products in healthy and diseased heartBrain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated TumorigenesisMTOR inhibition attenuates DNA damage and apoptosis through autophagy-mediated suppression of CREB1Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axisA circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficitsStrategies to overcome trastuzumab resistance in HER2-overexpressing breast cancers: focus on new data from clinical trials.Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinomaHow to take autophagy and endocytosis up a notch.Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.Notch signaling in glioblastoma: a developmental drug target?Osteopontin is Critical for Hyperactive mTOR-Induced Tumorigenesis in Oral Squamous Cell CarcinomaSTAT3 balances myocyte hypertrophy vis-à-vis autophagy in response to Angiotensin II by modulating the AMPKα/mTOR axis.Rapamycin prevents the development and progression of mutant epidermal growth factor receptor lung tumors with the acquired resistance mutation T790M.Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway.Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cowsRegulation of mTORC1 and its impact on gene expression at a glance.Akt1 mediates neuronal differentiation in zebrafish via a reciprocal interaction with notch signalingNotch-EGFR/HER2 Bidirectional Crosstalk in Breast CancerDeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulationDNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification.High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.ALDH2 in alcoholic heart diseases: molecular mechanism and clinical implications.p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.mTOR signaling in epilepsy: insights from malformations of cortical developmentPathway Regulation of p63, a Director of Epithelial Cell FatePositive feedback between oncogenic KRAS and HIF-1α confers drug resistance in colorectal cancerShared signaling pathways in normal and breast cancer stem cells.mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.Transcriptome Profiling of Caco-2 Cancer Cell Line following Treatment with Extracts from Iodine-Biofortified Lettuce (Lactuca sativa L.).Notch signaling and cardiac repair.The novel therapeutic effect of phosphoinositide 3-kinase-γ inhibitor AS605240 in autoimmune diabetes.EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.Effect of Nourishing "Yin" Removing "Fire" Chinese Herbal Mixture on Hypothalamic Mammalian Target of Rapamycin Expression during Onset of Puberty in Female Rats.A critical role for Rictor in T lymphopoiesis.
P2860
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P2860
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@ast
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@en
Mammalian target of rapamycin ...... TAT3/p63/Jagged/Notch cascade.
@nl
type
label
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@ast
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@en
Mammalian target of rapamycin ...... TAT3/p63/Jagged/Notch cascade.
@nl
prefLabel
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@ast
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@en
Mammalian target of rapamycin ...... TAT3/p63/Jagged/Notch cascade.
@nl
P2093
P2860
P356
P1476
Mammalian target of rapamycin ...... STAT3/p63/Jagged/Notch cascade
@en
P2093
David J Kwiatkowski
Guifang Cai
Haiyong Peng
Hongbing Zhang
Huangxuan Shen
Izabela Malinowska-Kolodziej
Jiahuai Han
Jianhui Ma
P2860
P304
P356
10.1172/JCI37964
P407
P577
2009-12-28T00:00:00Z