Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
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Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunctionIn cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin bindingSingle-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous EnvironmentThe RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long QT syndrome: a comprehensive open reading framDynamic, inter-subunit interactions between the N-terminal and central mutation regions of cardiac ryanodine receptorFörster resonance energy transfer measurements of ryanodine receptor type 1 structure using a novel site-specific labeling methodSubnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channelStructural and functional characterization of ryanodine receptor-natrin toxin interactionCatecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.FRET-based localization of fluorescent protein insertions within the ryanodine receptor type 1.Ryanodine receptors: structure, expression, molecular details, and function in calcium release.Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor.Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia.Single-particle cryo-EM of the ryanodine receptor channel in an aqueous environment.Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.Identification of ATP-binding regions in the RyR1 Ca²⁺ release channel.Ligand-dependent conformational changes in the clamp region of the cardiac ryanodine receptor.CLIC2-RyR1 interaction and structural characterization by cryo-electron microscopy.Two potential calmodulin-binding sequences in the ryanodine receptor contribute to a mobile, intra-subunit calmodulin-binding domain.Ryanodine receptor-mediated arrhythmias and sudden cardiac death.Conformational dynamics inside amino-terminal disease hotspot of ryanodine receptorLocalization of PKA phosphorylation site, Ser(2030), in the three-dimensional structure of cardiac ryanodine receptor.Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor.Ryanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction.IP(3) receptors: toward understanding their activation.The structural biology of ryanodine receptors.Ryanodine receptors: structure and function.Three-dimensional structure of recombinant type 1 inositol 1,4,5-trisphosphate receptor.Site-specific labeling of proteins for electron microscopy.
P2860
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P2860
Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Localization of an NH
@nl
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@ast
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@en
type
label
Localization of an NH
@nl
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@ast
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@en
prefLabel
Localization of an NH
@nl
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@ast
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@en
P2093
P2860
P356
P1476
Localization of an NH(2)-termi ...... he cardiac ryanodine receptor.
@en
P2093
Jeff Bolstad
Jing Zhang
Ruiwu Wang
S R Wayne Chen
Shitian Cai
Terence Wagenknecht
Wenqian Chen
P2860
P304
17785-17793
P356
10.1074/JBC.M700660200
P407
P50
P577
2007-04-23T00:00:00Z