Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities.
about
LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine.Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.Impact of Sample Matrix on Accuracy of Peptide Quantification: Assessment of Calibrator and Internal Standard Selection and Method Validation.Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro-in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques.Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathwayInteraction between oblongifolin C and UDP-glucuronosyltransferase isoforms in human liver and intestine microsomes.Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.Inhibition of low-grade inflammation by anthocyanins from grape extract in an in vitro epithelial-endothelial co-culture model.
P2860
Q33818825-49C68E5E-E392-42D8-A782-435CD64D6158Q36093125-86CBBABB-1536-4CA4-BC41-864136BEFB20Q36756623-C56ECCEE-5208-4308-B498-81F455E95637Q38537236-BB4FC93A-CFFC-4B96-910B-5CC86F1388D0Q38797489-EB689B41-48ED-4FEB-832C-531DB1357DBBQ39035538-170D9F00-395C-45AA-B13A-FCE0EB7F5198Q42184370-BD9A48AE-C647-48D6-ACB6-57EFD3D7ABA3Q53605610-D6D38AD4-1AB8-49CD-9CD7-39080ACE9858
P2860
Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Absolute quantification of UGT ...... ts glucuronidation activities.
@ast
Absolute quantification of UGT ...... ts glucuronidation activities.
@en
Absolute quantification of UGT ...... ts glucuronidation activities.
@nl
type
label
Absolute quantification of UGT ...... ts glucuronidation activities.
@ast
Absolute quantification of UGT ...... ts glucuronidation activities.
@en
Absolute quantification of UGT ...... ts glucuronidation activities.
@nl
prefLabel
Absolute quantification of UGT ...... ts glucuronidation activities.
@ast
Absolute quantification of UGT ...... ts glucuronidation activities.
@en
Absolute quantification of UGT ...... ts glucuronidation activities.
@nl
P2093
P2860
P1476
Absolute quantification of UGT ...... ts glucuronidation activities.
@en
P2093
P2860
P304
P356
10.1016/J.JPBA.2013.08.024
P577
2013-08-29T00:00:00Z