A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants. - Wikidata - awgldk - TriplyDB

A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

http://www.wikidata.org/entity/Q33569334

about

Research recommendations for selected IARC-classified agents Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention Mechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalate Human health effects of tetrachloroethylene: key findings and scientific issues Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity Nuclear receptors and pathogenesis of pancreatic cancer.Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro.A Comparative Study of Mouse Hepatic and Intestinal Gene Expression Profiles under PPARα Knockout by Gene Set Enrichment Analysis Plasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in Liver Regulation of mRNA Translation Is a Novel Mechanism for Phthalate Toxicity A systematic approach for identifying and presenting mechanistic evidence in human health assessments.The role of oxidative stress in carcinogenesis induced by metals and xenobiotics.Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.Occurrence of fibrates and their metabolites in source and drinking water in Shanghai and Zhejiang, China.PPARs Signaling and Cancer in the Gastrointestinal System.The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.

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P2860

A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

http://www.wikidata.org/entity/Q33569334

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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type

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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A reexamination of the PPAR-al ...... of environmental contaminants.

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Cheryl Siegel Scott

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Jane C Caldwell

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Jennifer Jinot

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Kathryn Z Guyton

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Rebecca C Brown

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Thomas F Bateson

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Weihsueh A Chiu

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cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN4119421

Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?

Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters

Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

WHO cooperative trial on primary prevention of ischaemic heart disease with clofibrate to lower serum cholesterol: final mortality follow-up. Report of the Committee of Principal Investigators

Peroxisome proliferator-activated receptors: structures and function

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1664-1672

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10.1289/EHP.0900758

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