Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

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Mechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalate Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells: an important role of early cytoskeleton disturbances in carcinogenesis?Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium Mono-(2-ethylhexyl) phthalate (MEHP) promotes invasion and migration of human testicular embryonal carcinoma cells Plasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in Liver The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.Regulation of mRNA Translation Is a Novel Mechanism for Phthalate Toxicity Phthalate exposure changes the metabolic profile of cardiac muscle cells.Obesity and metabolic comorbidities: environmental diseases?Proteome Characteristics of Non-Alcoholic Steatohepatitis Liver Tissue and Associated Hepatocellular Carcinomas.Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.Prenatal phthalate exposure: epigenetic changes leading to lifelong impact on steroid formation.A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure.The combined effects of DEHP and PCBs on phospholipase in the livers of mice.Activation of the Constitutive Androstane Receptor by Monophthalates Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.Comparative time course profiles of phthalate stereoisomers in mice.Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats.The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.DEHP induces obesity and hypothyroidism through both central and peripheral pathways in C3H/He mice.Impact of CAR agonist ligand TCPOBOP on mouse liver chromatin accessibility.

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P2860

Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

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http://www.wikidata.org/entity/Q37478119

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article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 October 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Characterization of peroxisome ...... ators in the rodent liver: di-

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Characterization of peroxisome ...... nstitutive-activated receptor.

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type

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Characterization of peroxisome ...... ators in the rodent liver: di-

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Characterization of peroxisome ...... nstitutive-activated receptor.

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Characterization of peroxisome ...... ators in the rodent liver: di-

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Characterization of peroxisome ...... nstitutive-activated receptor.

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Characterization of peroxisome ...... nstitutive-activated receptor.

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P2093

Beena Vallanat

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Carmen Wood

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Curtis D Klaassen

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Hongzu Ren

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J Christopher Corton

http://www.w3.org/2001/XMLSchema#string

Lauren M Aleksunes

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Michael H George

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P2860

PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

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p53-independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16alpha-carbonitrile.

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver

Effects of microsomal enzyme inducers on thyroid follicular cell proliferation and thyroid hormone metabolism.

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45-59

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scholarly article

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10.1093/TOXSCI/KFP251

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Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

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P2860

P2860

Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

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