Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase. - Wikidata - awgldk - TriplyDB

Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.

Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.

http://www.wikidata.org/entity/Q33569707

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SIRT1 links CIITA deacetylation to MHC II activation Inflammation and intracellular metabolism: new targets in OA The impact of cellular senescence in cancer therapy: is it true or not?Emerging regulators of the inflammatory process in osteoarthritis Senescence in adipose-derived stem cells and its implications in nerve regeneration Redox control of senescence and age-related disease New Insights for Oxidative Stress and Diabetes Mellitus Targeted In Situ Biosynthetic Transcriptional Activation in Native Surface-Level Human Articular Chondrocytes during Lesion Stabilization SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast.WISP1: Clinical insights for a proliferative and restorative member of the CCN family Pelvic irradiation does not increase the risk of hip replacement in patients with gynecological cancer. A cohort study based on 8,507 patients.Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy.Low-dose γ-radiation inhibits IL-1β-induced dedifferentiation and inflammation of articular chondrocytes via blockage of catenin signaling Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling Effect of Increasing Doses of γ-Radiation on Bone Marrow Stromal Cells Grown on Smooth and Rough Titanium Surfaces.G Protein-coupled Receptor 40 (GPR40) and Peroxisome Proliferator-activated Receptor γ (PPARγ): AN INTEGRATED TWO-RECEPTOR SIGNALING PATHWAY.Regeneration in the nervous system with erythropoietin Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1 H2O2 accumulation mediates differentiation capacity alteration, but not proliferative decline, in senescent human fetal mesenchymal stem cells.Radiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells.Ionizing radiation causes active degradation and reduces matrix synthesis in articular cartilage Effects of low dose X-ray irradiation on porcine articular cartilage explants.Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity.Regulation of SIRT1 in cellular functions: role of polyphenols Role of endothelin receptor A and NADPH oxidase in vascular abnormalities.Stem cell senescence and regenerative paradigms.Macro view of microRNA function in osteoarthritis.Epigenetics in osteoarthritis and its implication for future therapeutics.Epigenetic mechanisms and non-coding RNAs in osteoarthritis.Programming apoptosis and autophagy with novel approaches for diabetes mellitus.The current progress in understanding the molecular functions and mechanisms of visfatin in osteoarthritis.Harnessing the Power of SIRT1 and Non-coding RNAs in Vascular Disease.The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis.Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.Insulin-Like Growth Factor-1-Mediated DNA Repair in Irradiated Salivary Glands Is Sirtuin-1 Dependent.Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.

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P2860

Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.

http://www.wikidata.org/entity/Q33569707

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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type

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

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prefLabel

Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

@ast

Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

@en

Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

@nl

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Journal of Biological Chemistry

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Ionizing radiation induces cel ...... lation of SIRT1 by p38 kinase.

@en

P2093

Eun-Hee Hong

http://www.w3.org/2001/XMLSchema#string

Hong-Duck Um

http://www.w3.org/2001/XMLSchema#string

Jae-Hong Kim

http://www.w3.org/2001/XMLSchema#string

Jae-Sung Kim

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Jong-Il Kim

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Kee-Ho Lee

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Sang-Gu Hwang

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Song-Ja Kim

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Su-Jae Lee

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P2860

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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1283-1295

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10.1074/JBC.M109.058628

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285

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2009-11-03T00:00:00Z

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19887452

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2801256

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