The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
about
Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7Interactions of the human MCM-BP protein with MCM complex components and Dbf4CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeastThe replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?Structural Mechanisms of Hexameric Helicase Loading, Assembly, and UnwindingMechanisms for initiating cellular DNA replicationNew insights into replisome fluidity during chromosome replicationGenomic instability in cancer.A Role for USP7 in DNA ReplicationCrystal structure of human CDC7 kinase in complex with its activator DBF4The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.Mcm2 phosphorylation and the response to replicative stressCdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complexMechanisms Governing DDK Regulation of the Initiation of DNA ReplicationAn Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication InitiationHelicase loading at chromosomal origins of replicationA high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage responseThe Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation.Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases.RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cellsA quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations.Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionDomain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression.DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damageA unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNAThe role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator.Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG componentsHighly stable loading of Mcm proteins onto chromatin in living cells requires replication to unloadA Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress.Arabidopsis thaliana MCM2 plays role(s) in mungbean yellow mosaic India virus (MYMIV) DNA replication.Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiationGenomic approaches to the initiation of DNA replication and chromatin structure reveal a complex relationshipArchaeology of eukaryotic DNA replication
P2860
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P2860
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@ast
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@en
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.
@nl
type
label
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@ast
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@en
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.
@nl
prefLabel
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@ast
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@en
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.
@nl
P2860
P356
P1433
P1476
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
@en
P2093
Yi-Jun Sheu
P2860
P2888
P304
P356
10.1038/NATURE08647
P407
P577
2010-01-01T00:00:00Z
P5875
P6179
1022812644